| 编号: | 135857 |
| 中文名称: | 五肽JKC-301 |
| 英文名: | Cyclo(-D-Asp-Pro-D-Ile-Leu-D-Trp) |
| CAS号: | 136553-96-3 |
| 单字母: | cyclo(dPiLw)(main chain cyclo) |
| 三字母: | cyclo(DAsp-Pro-DIle-Leu-DTrp)(main chain cyclo) |
| 氨基酸个数: | 5 |
| 分子式: | C32H44N6O7 |
| 平均分子量: | 624.73 |
| 精确分子量: | 624.33 |
| 等电点(PI): | 6.26 |
| pH=7.0时的净电荷数: | -0.02 |
| 平均亲水性: | -1 |
| 疏水性值: | 0.46 |
| 消光系数: | 5500 |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 大内皮素及类似物 |
JKC-301, a highly potent ET-A receptor antagonist.
| DOI | 名称 | |
|---|---|---|
| 10.1002/art.21572 | Signaling pathways regulating intercellular adhesion molecule 1 expression by endothelin 1: comparison with interleukin-1beta in normal and scleroderma dermal fibroblasts | 下载 |
| 10.1111/j.1476-5381.1996.tb15652.x | Characterization of [125I]-endothelin-1 and [125I]-BQ3020 binding to rat cerebellar endothelin receptors | 下载 |
| 10.1124/mol.52.4.582 | Identification and characterization of a novel endothelin receptor that binds both ETA- and ETB-selective ligands | 下载 |
