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909409-86-5,Alarin (human),H2N-Ala-Pro-Ala-His-Arg-Ser-Ser-Thr-Phe-Pro-Lys-Trp-Val-Thr-Lys-Thr-Glu-Arg-Gly-Arg-Gln-Pro-Leu-Arg-Ser-COOH,H2N-APAHRSSTFPKWVTKTERGRQPLRS-OH,杭州专肽生物的产品

Alarin (human)

衍生自甘丙肽样肽(GALP)RNA的剪接变体。

编号:110847

CAS号:909409-86-5

单字母:H2N-APAHRSSTFPKWVTKTERGRQPLRS-OH

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  • 编号:110847
    中文名称:Alarin (human)
    CAS号:909409-86-5
    单字母:H2N-APAHRSSTFPKWVTKTERGRQPLRS-OH
    三字母:H2N

    N端氨基

    -Ala

    丙氨酸

    -Pro

    脯氨酸

    -Ala

    丙氨酸

    -His

    组氨酸

    -Arg

    精氨酸

    -Ser

    丝氨酸

    -Ser

    丝氨酸

    -Thr

    苏氨酸

    -Phe

    苯丙氨酸

    -Pro

    脯氨酸

    -Lys

    赖氨酸

    -Trp

    色氨酸

    -Val

    缬氨酸

    -Thr

    苏氨酸

    -Lys

    赖氨酸

    -Thr

    苏氨酸

    -Glu

    谷氨酸

    -Arg

    精氨酸

    -Gly

    甘氨酸

    -Arg

    精氨酸

    -Gln

    谷氨酰胺

    -Pro

    脯氨酸

    -Leu

    亮氨酸

    -Arg

    精氨酸

    -Ser

    丝氨酸

    -OH

    C端羧基

    氨基酸个数:25
    分子式:C127H205N43O35
    平均分子量:2894.25
    精确分子量:2892.56
    等电点(PI):12.99
    pH=7.0时的净电荷数:6.21
    平均亲水性:0.48571428571429
    疏水性值:-1.29
    消光系数:5500
    来源:人工化学合成,仅限科学研究使用,不得用于人体。
    储存条件:负80℃至负20℃
    标签:未分类肽   

  • Alarin, APAHRSSTFPKWVTKTERGRQPLRS, is derived from a splice variant of galanin-like peptide (GALP) RNA. It shows potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, as was also observed with other members of the galanin peptide family. Since alarin only shares five amino acids with GALP it is unlikely that the peptide can activate GALP-specific receptors. The neuropeptide has been reported to be expressed in ganglionic cells of human neuroblastic tumors and might therefore represent a potential tumor marker. Bachem provides this product solely for uses within the scope of any statute or law providing for an immunity, exemption, or exception to patent infringement (“Exempted Uses”), including but not limited to 35 U.S.C. § 271(e)(1) in the United States, the Bolar type exemption in Europe, and any corresponding exception to patent infringement in any other country. It is the sole responsibility of the purchaser or user of this product, and the purchaser or user of this product agrees to engage only in such Exempted Uses, and to comply with all applicable intellectual property laws and/or regulations. The purchaser of this product agrees to indemnify Bachem against all claims in connection with the performance of the respective commercial agreement (e.g. supply agreement) and possible infringements of intellectual property rights.

  • DOI名称
    10.1385/JMN:29:2:145Gangliocytes in neuroblastic tumors express alarin, a novel peptide derived by differential splicing of the galanin-like peptide gene下载
    10.1073/pnas.0608585104Alarin is a vasoactive peptide下载
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