报告人：李继承教授（浙江大学细胞生物学研究所所长，浙江大学医学院人体解剖学与细胞生物学系主任）

讲座题目：

1.  Biomedical Research Writing for Publication, Specific Tips on AR

2.  肺结核早期诊断和证候血清蛋白质组学研究

时间：2010年12月9日下午3点半

地点：生命科学学院三楼多功能厅

生命科学学院

江苏省分子医学生物技术重点实验室

李继承教授简介：

男，1957年生，浙江大学教授，博士生导师，现任浙江大学细胞生物学研究所所长，人体解剖学与细胞生物学系主任，中国细胞生物学会常务理事，美国The Anatomical Record杂志亚洲副主编，国家自然科学基金委理科基地“十二五纲要”编写组基础医学、心理学、中医、中药召集人。共主持研究国家自然科学基金等国家级项目10项，发表SCI论文80余篇。1999年获国务院颁发的政府特殊津贴，2001年获中国高校自然科学一等奖。

研究方向

主要研究兴趣是肿瘤淋巴转移相关基因的表观遗传学；天然药物诱导肿瘤细胞凋亡与相关基因突变;重大疾病的蛋白组学；淋巴孔调控因子与信号转导途径和先天性巨结肠的分子遗传学研究。

近期文章：

1.        Li M, Chen F, Liu CP; Li DM, Li X, Wang C, Li JC. Dexamethasone enhances trichosanthin-induced apoptosis in the HepG2 hepatoma cell line. Life Sci. 2010, 86（1）10－16.

2.        Cui-Ping Liu, Xin-Gang Li, Jin-Tu Lou, YunXue, Chun-Fen Luo, Xue-Wu Zhou, Fei-Chen, Xiang Li, Meng Li, Ji-Cheng Li. Association analysis of the PHOX2B  gene with Hirschsprung disease in the Han Chinese population of Southeastern China. Journal of Pediatric Surgery  2009;44(9):1805-1811

3.        Dun-Hong, Hai-Xiao Chen,Yun Xue, Dong-Mei Li, Xiao-Chen Wan, Renshan Ge, Ji-Cheng Li. Osteoblastogenic effects of dexamethasone through upregulation of TAZ expression in rat mesenchymal stem cells. Journal of Steroid Biochemistry & Molecular Biology 2009;116:86–92

4.        Marong Fang, Zhiying Hu, Yan Li, Ji-Cheng Li, David T Yew. Nestin positive cells in the retina and spinal cord of the sturgeon after hypoxia. International Journal of Neuroscience 2009;119-460

5.        Lei Jiang, Yangchao Chen, Chu-yan Chan, Xin Wang, Lin Lind, Ming-liang He, Marie C.M. Line, David T. Yew, Joseph J.Y. Sung, Ji-Cheng Li*, Hsiang-fu Kung*. Down-regulation of stathmin is required for TGF-β inducible early gene 1 induced growth inhibition of pancreatic cancer cells. Cancer Letters, 2009;274:101-108.

6.        Yingyu Ma, Liang Wu, Cuiping Liu, Liqian Xu, Dongmei Li and Ji-Cheng Li. The correlation of genetic instability of PINX1 gene to clinico- pathological features of gastric cancer in the Chinese population. J Cancer Res Clin Oncol. 2009, 135(3):431-7

7.        Ping Wang, Li-Li Chen, Hui Yan, Ji-Cheng Li. Trichosanthin suppresses Hela cell proliferation through inhibition of the PKC/MAPK signaling pathway. Cell Biol Toxicol 2009；25：479－488

8.        Xiao-Chen Wan ,Cui-Ping Liu ,Meng Li ,Dun Hong, Dong-Mei Li a, Hai-Xiao Chen, Ji-Cheng Li. Staphylococcal enterotoxin C injection in combination with ascorbic acid promotes the differentiation of bone marrow-derived mesenchymal stem cells into osteoblasts In vitro. Biochemical and Biophysical Research Communications 2008；373：488–492.

9.        Cuiping Liu, Lei Jin, Hui Li, Jintu Lou, Chunfen Luo, Xuewu Zhou ,Ji-Cheng Li. RET polymorphisms and the risk of Hirschsprung’s disease in a Chinese population. J Hum Genet 2008；53:825–833.

10.     Dun Hong, Hai-Xiao Chen, Ren-Shan Ge, Ji-Cheng Li. The biological roles of extracellular and intracytoplasmic glucocorticoids in skeletal cells. Journal of Steroid Biochemistry & Molecular Biology 2008; 111:164–170