2014.03.28，Professor Shi Yunyu/Wu Jihui Published a paper entitled:“Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding” in Cell Research,online
时间：2021-04-12 21:15:01学院：生命科学学院学校：中国科学技术大学
Author：Wang Juncheng、Qin Su、LI Fudong、Li Sai、Zhang Wei、Peng Junhui、Zhang Zhiyong、Gong Qingguo、Wu Jihui、Shi Yunyu
Abstract:The eukaryotic genome is packed into highly compacted chromatin, the basic unit of which is a nucleosome composed of 147 base pairs of DNA wrapped around the histone octamer. Post-translational modifications along histone N-terminal tails can be recognized by various 'reader' modules. PWWP domain, one type of 'reader' modules, has been identified to recognize H3K36me3 in the peptide and nucleosome context.
http://dx.doi.org/10.1038/cr.2014.38
版权与免责声明：本网页的内容由收集互联网上公开发布的信息整理获得。目的在于传递信息及分享，并不意味着赞同其观点或证实其真实性，也不构成其他建议。仅提供交流平台，不为其版权负责。如涉及侵权，请联系我们及时修改或删除。邮箱：sales@allpeptide.com