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一种含10个氨基酸的神经肽,属于蛙肽家族,为铃蟾肽相关肽。
编号:159341
CAS号:87096-84-2
单字母:H2N-GNLWATGHFM-CONH2
Neuromedin B 是一种含10个氨基酸的神经肽,属于蛙肽家族,为铃蟾肽相关肽。
Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals.
Neuromedin B is a neuropeptide that has been shown to activate the TRPC ion channels in mammalian cells. It also has been shown to bind to receptors and have a potent effect on cell biology, as well as being used as a research tool for studying protein interactions. Neuromedin B is found in humans, pigs, and rats, where it is expressed primarily in the brain and gastrointestinal tract. This peptide has been shown to be an inhibitor of some types of ion channels.
Neuromedin C (NMC) is a peptide that belongs to the family of neuromedin and is a potent activator of ion channels. It has been shown to be a ligand for opioid receptors, which may be due to its ability to inhibit the release of neurotransmitters such as acetylcholine and noradrenaline. Neuromedin C has also been shown to inhibit the binding of morphine-6 beta-glucuronide in rat brain synaptosomes. In addition, NMC has been reported as an inhibitor of cell proliferation and induce apoptosis in various cancer cells including colon and prostate cancers.\n\nNeuromedin C is a potent activator of ion channels that can bind with opioid receptors. It inhibits the release of neurotransmitters such as acetylcholine and noradrenaline and also inhibits binding with morphine-6 beta-glucuronide in rat brain synaptosomes. Furthermore, it induces apoptosis
DOI | 名称 | |
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10.1016/s0301-0082(00)00004-6 | Neuromedin B | 下载 |
编号 | 名称 | CAS号 |
116485 | 神经调节肽Neuromedin(β-30) | |
H2N-LSWDLPEPRSRAGKIRVHPRGNLWATGHFM-CONH2 | ||
147515 | 神经调节肽Biotin-Neuromedin B | |
Biotinyl-GNLWATGHFM-CONH2 | ||
201718 | 荧光标记的神经肽FITC-TAT-Neuromedin B | |
5FITC-Ahx-GRKKRRQRRRPPQGNLWATGHFM-CONH2 | ||
荧光标记的神经肽B |