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专注多肽 服务科研
编号: | 568860 |
中文名称: | [Asu16]Oxytocin |
英文名: | [Asu16]Oxytocin |
CAS号: | 14317-68-1 |
单字母: | H2N-YIQN-Asu-PLG-CONH2 |
三字母: | cyclo(Tyr-Ile-Gln-Asn-Asu)-Pro-Leu-Gly-CONH2,主侧成环 |
氨基酸个数: | 8 |
分子式: | C45H71N11O12 |
平均分子量: | 958.11 |
精确分子量: | 957.53 |
等电点(PI): | - |
pH=7.0时的净电荷数: | 1.97 |
平均亲水性: | -1.32 |
疏水性值: | -0.23 |
外观与性状: | 白色粉末状固体 |
消光系数: | 1490 |
来源: | 人工化学合成,仅限科学研究使用,不得用于人体。 |
纯度: | 95%、98% |
盐体系: | 可选TFA、HAc、HCl或其它 |
生成周期: | 2-3周 |
储存条件: | 负80℃至负20℃ |
标签: | 缩宫素(Oxytocin) 氨基酸衍生物肽 |
Oxytocin is a peptide hormone and neurotransmitter. It is primarily used in the brain to regulate social behavior, such as maternal behaviour, sexual arousal and romantic attachment. Oxytocin is also used for uterine contractions during childbirth and to induce labour. Oxytocin can be administered by injection or as nasal spray. It has a half-life of about two minutes in the blood stream and its effects last up to one hour. Oxytocin is a nonapeptide with the amino acid sequence: Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-Leu-Met-(OH). The oxytocin receptor (OXTR) belongs to G protein coupled receptors (GPCR), which are known for their roles in cell signaling, oncogenesis, immunity, inflammation, pain sensation and endocrine regulation. The OXTR is expressed throughout the body including the uterus and vagina.