序列 RLIEDNEYTARG 对应于劳斯肉瘤病毒编码的转化蛋白 pp60 src 中报道的酪氨酸磷酸化位点(即氨基酸 412-422)的序列。肽的体外酪氨酸磷酸化受到表皮生长因子的刺激。
编号:194406
CAS号:81493-98-3
单字母:H2N-RRLIEDNEYTARG-OH
The sequence RLIEDNEYTARG corresponds to the sequence of the reported site of tyrosine phosphorylation (i.e. amino acids 412-422) in the Rous sarcoma virus-encoded transforming protein pp60 src. In vitro tyrosine phosphorylation of the peptide is stimulated by epidermal growth factor.
DOI | 名称 | |
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10.1073/pnas.79.5.1443 | Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranes | 下载 |
10.1111/j.1399-3011.1998.tb00424.x | The design, synthesis and activity of pentapeptide pp60c-src inhibitors containing L-phosphotyrosine mimics | 下载 |