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凝血酶受体激动剂 TRAP-7,SFLLRNP,对应于凝血酶受体的 42-48 位残基。在某些 T 细胞系中,TRAP-7 在诱导 Ca²⁺ 动员和蛋白激酶 C 活化方面与凝血酶一样有效。
编号:151146
CAS号:145229-76-1
单字母:H2N-SFLLRNP-OH
| 参考文献(References): | B.Mari et al., J. Biol. Chem., 269, 8517 (1994) Molloy, C. et al. J. Clin. Invest. 97, 1173 (1996) Ishida, A. et al. FEBS Lett. 427, 155 (1998) Ishida, A. and H. Fujisawa, J. Biol. Chem. 270, 2163 (1995) |
凝血酶受体激动剂TRAP-7,SFLLRNP,对应于凝血酶受体的残基42-48。TRAP-7在诱导Ca²方面与凝血酶一样有效⁺ 一些T细胞系中的动员和蛋白激酶C活化。
The thrombin receptor agonist TRAP-7, SFLLRNP, corresponds to residues 42-48 of the thrombin receptor. TRAP-7 is as effective as thrombin in inducing Ca²⁺ mobilization and protein kinase C activation in some T cell lines.
H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-OH是一种具有显着细胞毒性的生物相容性聚合物。它是一种治疗传染病、癌症和大脑功能的药物。该聚合物已被证明在动脉粥样硬化的实验模型中是有效的,并且在低剂量组中也诱导神经元死亡。H-Ser-Phe-Leu-Leu-Arg-Asn Pro-OH是一种信号肽,参与细胞增殖,凋亡和血管生成等生理作用。
H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-OH is a biocompatible polymer that has significant cytotoxicity. It is a pharmacological treatment for infectious diseases, cancer, and brain functions. This polymer has been shown to be effective in the experimental model of atherosclerosis and also induces neuronal death in the low dose group. H-Ser-Phe-Leu-Leu-Arg-Asn Pro OH is a signal peptide that is involved in physiological effects such as cell proliferation, apoptosis, and angiogenesis.
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