Formally derived from the C-terminal dipeptide of oxytocin., cyclo(Leu-Gly) is active in memory processes. The diketopiperazine blocks the narcotic-induced dopamine receptor supersensitivity.
编号：189233
CAS号：5845-67-0
单字母：cyclo(GL)(main chain cyclo)
| 编号: | 189233 |
| 中文名称: | 环二肽cyclo(Gly-Leu) |
| 英文名: | c(Gly-Leu) |
| 英文同义词: | c(Leu-Gly)、cyclo(Leu-Gly) |
| CAS号: | 5845-67-0 |
| 单字母: | cyclo(GL)(main chain cyclo) |
| 三字母: | cyclo(Gly-Leu)(main chain cyclo) |
| 氨基酸个数: | 2 |
| 分子式: | C8H14N2O2 |
| 平均分子量: | 170.21 |
| 精确分子量: | 170.11 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 0.97 |
| 平均亲水性: | -1.8 |
| 疏水性值: | 1.7 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 修饰类型: | 酰胺键成环 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 环二肽 现货多肽 |
Formally derived from the C-terminal dipeptide of oxytocin., cyclo(Leu-Gly) is active in memory processes. The diketopiperazine blocks the narcotic-induced dopamine receptor supersensitivity.
环二肽又叫2,5-二酮哌嗪的衍生物,作为环肽成员中最小的一类环肽，专肽生物有部分环二肽的现货，也可以根据实验需求，定制含D型与L型，S与R构型的氨基酸。
| DOI | 名称 | |
|---|---|---|
| 10.1271/bbb.110590 | Kinetic analysis for the degradation of glycyl-L-leucine and L-leucyl-glycine in subcritical water | 下载 |
| 10.1038/nchembio.1868 | Analysis of 51 cyclodipeptide synthases reveals the basis for substrate specificity | 下载 |
