13433-09-5_二肽Asp-Phe_H2N-Asp-Phe-OH_H2N-DF-OH_600+种二肽(Dipeptide)现货

二肽Asp-Phe
Aspartame Impurity B, saponofication product of aspartame.

编号：197925

CAS号：13433-09-5

单字母：H2N-DF-OH

编号:	197925
中文名称:	二肽Asp-Phe
英文名:	Asp-Phe
CAS号:	13433-09-5
单字母:	H2N-DF-OH
三字母:	H2N N端氨基：N-terminal amino group。在肽或多肽链中含有游离a-氨基的氨基酸一端。在表示氨基酸序列时，通常将N端放在肽链的左边。 -Asp L-天冬氨酸：aspartic acid。系统命名为(2S)-氨基-丁二酸。是编码氨基酸，又是神经递质。符号：D，Asp。D-天冬氨酸存在于多种细菌的细胞壁和短杆菌肽A中。 -Phe L-苯丙氨酸：phenylalanine。系统命名为(2S)-氨基-3-苯基丙酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：F，Phe。 -OH C端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。
氨基酸个数:	2
分子式:	C₁₃H₁₆N₂O₅
平均分子量:	280.28
精确分子量:	280.11
等电点(PI):	6.26
pH=7.0时的净电荷数:	-0.02
平均亲水性:	0.25
疏水性值:	-0.35
外观与性状:	白色粉末状固体
消光系数:	-
来源:	人工化学合成，仅限科学研究使用，不得用于人体。
纯度:	95%、98%
盐体系:	可选TFA、HAc、HCl或其它
生成周期:	2-3周
储存条件:	负80℃至负20℃
标签:	600+种二肽(Dipeptide)现货

Aspartame Impurity B, saponofication product of aspartame.

H-Asp-Phe-OH is a diagnostic agent that contains the amino acid aspartame and a hydroxyl group. It is hydrolyzed in the body to form aspartic acid, phenylalanine, and methanol. The methyl ester of H-Asp-Phe-OH is hydrochloride. This compound has been used to study locomotor activity in mice and rats. Aspartame has also been shown to be an inhibitor of certain enzymes, such as fatty acid synthase, which is associated with human pathogens. The lc-ms/ms method has been used to detect H-Asp-Phe-OH metabolites in human serum samples. In addition, this compound can be used for the diagnosis of diseases such as diabetes mellitus type 2 and Alzheimer’s disease by measuring uptake into cells at enzyme activities.

DOI	名称
10.1021/bi050008r	Mechanism of the reaction catalyzed by isoaspartyl dipeptidase from Escherichia coli	下载
10.1021/bi901397h	The human asparaginase-like protein 1 hASRGL1 is an Ntn hydrolase with beta-aspartyl peptidase activity	下载
10.1093/jn/119.5.713	Identification of N-beta-L-aspartyl-L-phenylalanine as a normal constituent of human plasma and urine	下载
10.1021/ja01038a046	Structure-taste relationships of some dipeptides	下载