37462-92-3_二肽Ile-Pro_H2N-Ile-Pro-OH_H2N-IP-OH_600+种二肽(Dipeptide)现货

二肽Ile-Pro
猪二肽基肽酶 IV (DPP IV) 的竞争性抑制剂，IC₅₀ 0.015 mM。

编号：186508

CAS号：37462-92-3

单字母：H2N-IP-OH

编号:	186508
中文名称:	二肽Ile-Pro
英文名:	Ile-Pro
CAS号:	37462-92-3
单字母:	H2N-IP-OH
三字母:	H2N N端氨基：N-terminal amino group。在肽或多肽链中含有游离a-氨基的氨基酸一端。在表示氨基酸序列时，通常将N端放在肽链的左边。 -Ile L-异亮氨酸：isoleucine。系统命名为(2S)-氨基-(3R)-甲基戊酸。是编码氨基酸。有两个手性碳原子，是哺乳动物的必需氨基酸。符号:I，Ile。 -Pro L-脯氨酸：proline。系统命名为吡咯烷-(2S)-羧酸。为亚氨基酸。是编码氨基酸。在肽链中有特殊作用，如易形成顺式的肽键等。符号：P，Pro。 -OH C端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。
氨基酸个数:	2
分子式:	C₁₁H₂₀N₂O₃
平均分子量:	228.29
精确分子量:	228.15
等电点(PI):	-
pH=7.0时的净电荷数:	0.97
平均亲水性:	-1.8
疏水性值:	1.45
外观与性状:	白色粉末状固体
消光系数:	-
来源:	人工化学合成，仅限科学研究使用，不得用于人体。
纯度:	95%、98%
盐体系:	可选TFA、HAc、HCl或其它
生成周期:	2-3周
储存条件:	负80℃至负20℃
标签:	600+种二肽(Dipeptide)现货

Competitive inhibitor of porcine dipeptidyl peptidase IV (DPP IV), IC₅₀ 0.015 mM.

H-Ile-Pro-OH is an amino acid that is a constituent of sphingolipids, which are important for the metabolism of lipids and other biological substances. H-Ile-Pro-OH can be found in casein as well as oxidation products of casein. It has been used in diagnostic tests to measure levels of hippuric acid in plasma samples. The dietary intake of H-Ile-Pro-OH can be determined by measuring the concentration of this amino acid in plasma samples. Synthetic H-Ile-Pro-OH can also be used for studies on the metabolism of tryptophan. This amino acid has been shown to inhibit chloride ion transport across the cell membrane and fatty acid synthesis, as well as proteolysis and protein degradation by pancreatic enzymes.

DOI	名称
10.1016/j.foodchem.2012.02.183	Production of dipeptidyl peptidase IV inhibitory peptides from defatted rice bran	下载
10.1007/0-306-47920-6_8	Different inhibition mechanisms of dipeptidyl peptidase IV by tryptophan containing peptides and amides	下载
10.1128/JB.186.5.1398-1408.2004	Relevance of peptide uptake systems to the physiology and virulence of Streptococcus agalactiae	下载
10.1111/jnc.13624	Neuropeptide Y (NPY) in cerebrospinal fluid from patients with Huntington's Disease: increased NPY levels and differential degradation of the NPY1-30 fragment	下载