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专注多肽 服务科研

| 参考文献(References): | K.Mizuno et al., Biochem. Biophys. Res. Commun., 97, 1283 (1980) |
牛肾上腺髓质甲硫氨酸脑啡肽的前体。
Bovine adrenomedullary Met-enkephalin precursor.
BAM-12P是一种与CXCR4趋化因子受体胞外结构域结合的肽。它是该受体的抑制剂,并已证明能在体外抑制HIV-1感染。BAM-12P还已被证明在某些细胞系中作为CXCR4受体的激活剂,可用作研究配体对受体影响的研究工具。BAM-12P是通过化学合成的高纯度物质,其CAS号为75513-71-2。它从杆状病毒表达系统中分离得到。
BAM-12P is a peptide that binds to the extracellular domain of the CXCR4 chemokine receptor. It is an inhibitor of this receptor, and has been shown to inhibit HIV-1 infection in vitro. BAM-12P has also been shown to act as an activator of the CXCR4 receptor in some cell lines, and can be used as a research tool for studying the effects of ligands on receptors. BAM-12P is chemically synthesized with high purity and its CAS number is 75513-71-2. It was isolated from the baculovirus expression system.
| DOI | 名称 | |
|---|---|---|
| 10.1016/s0006-291x(80)80005-2 | A new family of endogenous "big" Met-enkephalins from bovine adrenal medulla: purification and structure of docosa- (BAM-22P) and eicosapeptide (BAM-20P) with very potent opiate activity | 下载 |





