70996-06-4_标记肽Glutaryl-GGF-7-氨基-4-甲基香豆素_Glutaryl-Gly-Gly-Phe-AMC_Glutaryl-GGF-AMC_AMC修饰肽_ 三肽

标记肽Glutaryl-GGF-7-氨基-4-甲基香豆素
胰凝乳蛋白酶的敏感荧光底物。

编号：154388

CAS号：70996-06-4

单字母：Glutaryl-GGF-AMC

编号:	154388
中文名称:	标记肽Glutaryl-GGF-7-氨基-4-甲基香豆素
英文名:	Glutaryl-Gly-Gly-Phe-AMC
CAS号:	70996-06-4
单字母:	Glutaryl-GGF-AMC
三字母:	Glutaryl N端戊二酸修饰 -Gly 甘氨酸：glycine。系统命名为 2-氨基乙酸。是编码氨基酸中没有旋光性的最简单的氨基酸，因具有甜味而得名。符号：G，Gly。 -Gly 甘氨酸：glycine。系统命名为 2-氨基乙酸。是编码氨基酸中没有旋光性的最简单的氨基酸，因具有甜味而得名。符号：G，Gly。 -Phe L-苯丙氨酸：phenylalanine。系统命名为(2S)-氨基-3-苯基丙酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：F，Phe。 -AMC 7-氨基-4-甲基香豆素（AMC或Amc）是一种荧光染料，其激发波长为350纳米，发射波长为450纳米。
氨基酸个数:	3
分子式:	C₂₈H₃₀O₈N₄
平均分子量:	550.56
精确分子量:	550.21
等电点(PI):	-
pH=7.0时的净电荷数:	-
平均亲水性:	-2.5
疏水性值:	0.67
消光系数:	-
来源:	人工化学合成，仅限科学研究使用，不得用于人体。
盐体系:	可选TFA、HAc、HCl或其它
储存条件:	负80℃至负20℃
标签:	AMC修饰肽 三肽

Glutaryl-Gly-Gly-Phe-AMC is a proteolytic peptide which is used in the study of the proteasome. It has been shown to have affinity for the proteasome, and can be used as a monoclonal antibody for both immunohistochemical analysis and two-dimensional electrophoresis. The peptide was sequenced and found to have no homology to any known protein or peptide. Glutaryl-Gly-Gly-Phe-AMC has been shown to bind specifically to β amyloid (Aβ) subunits in cell homogenates and cytosol, as well as nuclei in tissue sections from AD brain. In addition, it has been shown that this peptide can be fluorescently labeled with Alexa Fluor 488 or 594 dye for use in microscopy studies.

7-氨基-4-甲基香豆素（AMC或Amc）是一种荧光染料，其激发波长为350纳米，发射波长为450纳米。

7-Amino-4-methyl-coumaride (AMC or Amc) is fluorophor with an excitation at 350 nm and emission of 450 nm .
Glt-GGF-AMC, sensitive fluorogenic substrate for chymotrypsin.
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