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Ac-Leu-Arg-Gly-Gly-CHO

编号:573351

CAS号:

单字母:Ac-LRGG-CHO

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  • 编号:573351
    中文名称:Ac-Leu-Arg-Gly-Gly-CHO
    单字母:Ac-LRGG-CHO
    三字母:Ac

    N端乙酰化封端,一种常见的修饰方式,常用于模拟蛋白质中的肽片段。

    -Leu

    L-亮氨酸:leucine。系统命名为(2S)-氨基-4-甲基戊酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号:L,Leu。

    -Arg

    L-精氨酸:arginine。系统命名为(2S)-氨基-5-胍基戊酸。在生理条件下带正电荷,为编码氨基酸。是幼小哺乳动物的必需氨基酸。符号:R,Arg。

    -Gly

    甘氨酸:glycine。系统命名为 2-氨基乙酸。是编码氨基酸中没有旋光性的最简单的氨基酸,因具有甜味而得名。符号:G,Gly。

    -Gly

    甘氨酸:glycine。系统命名为 2-氨基乙酸。是编码氨基酸中没有旋光性的最简单的氨基酸,因具有甜味而得名。符号:G,Gly。

    -CHO

    C端醛基化,醛基亦称甲酰基。

    氨基酸个数:4
    分子式:C18H33O5N7
    平均分子量:427.5
    精确分子量:427.25
    等电点(PI):-
    pH=7.0时的净电荷数:1
    平均亲水性:0.6
    疏水性值:-0.38
    消光系数:-
    来源:人工化学合成,仅限科学研究使用,不得用于人体。
    纯度:95% 或98%可选
    盐体系:若定制,可选TFA盐、醋酸盐、盐酸盐和柠檬酸盐等
    生成周期:现货或定制2-3周,请咨询销售人员
    储存条件:负80℃至负20℃
    标签:醛肽   

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    Peptide Ac-LRGG-CHO is a Research Peptide with significant interest within the field academic and medical research. Recent citations using Ac-LRGG-CHO include the following: Ubiquitin-Derived Fragment as a Peptide Linker for the Efficient Cleavage of a Target Protein from a Degron Y Utsugi, K Nishimura , S Yamanaka - ACS Chemical , 2024 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acschembio.3c00670 Prokaryotic Expression and Functional Verification of Antimicrobial Peptide LRGG X Liu, YN Ding, YH Shen, SZ Liu, YH Liu, YT Wang - 2024 - preprints.orghttps://www.preprints.org/manuscript/202405.1656 Cynoglossus semilaevis ISG15: A Secreted Cytokine-Like Protein That Stimulates Antiviral Immune Response in a LRGG Motif-Dependent Manner W Wang , M Zhang, Z Xiao, L Sun - 2012 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044884 Quantitative proteomics to decipher ubiquitin signaling PC Chen , CH Na , J Peng - Amino acids, 2012 - Springerhttps://link.springer.com/article/10.1007/s00726-012-1286-y The ubiquitin E1 activating enzyme Ube1 mediates NEDD8 activation under diverse stress conditions O Leidecker , I Matic, B Mahata, EPDP Xirodimas - researchgate.nethttps://www.researchgate.net/profile/Bidesh-Mahata/publication/221866678_The_ubiquitin_E1_enzyme_Ube1_mediates_NEDD8_activation_under_diverse_stress_conditions/links/551bc6390cf20d5fbde20d28/The-ubiquitin-E1-enzyme-Ube1-mediates-NEDD8-activation-under-diverse-stress-conditions.pdf Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry NJ Denis, J Vasilescu, JP Lambert , JC Smith - , 2007 - Wiley Online Libraryhttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/pmic.200600410 Design and evaluation of a novel peptide-drug conjugate covalently targeting SARS-CoV-2 papain-like protease N Liu, Y Zhang, Y Lei, R Wang, M Zhan - Journal of Medicinal , 2022 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.1c02022 Electrospray ionization tandem mass spectrometry of model peptides reveals diagnostic fragment ions for protein ubiquitination MR Esteban Warren, CE Parker - Journal Devoted to , 2005 - Wiley Online Libraryhttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/rcm.1798 Human serum amyloid A3 peptide enhances intestinal MUC3 expression and inhibits EPEC adherence MA Larson , SH Wei, A Weber, DR Mack - Biochemical and , 2003 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0006291X02029017 New insights into host-parasite ubiquitin proteome dynamics in P. falciparum infected red blood cells using a TUBEs-MS approach L Mata-Cantero, M Azkargorta, F Aillet , W Xolalpa - Journal of , 2016 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1874391916300598 Complementary deoxyribonucleic acid sequence encoding bovine ubiquitin cross-reactive protein: a comparison with ubiquitin and a 15-kDa ubiquitin homolog KJ Austin, JK Pru, TR Hansen - Endocrine, 1996 - Springerhttps://link.springer.com/article/10.1007/BF02738706 UbiGate: a synthetic biology toolbox to analyse ubiquitination K Kowarschik, W Hoehenwarter , S Marillonnet - new , 2018 - Wiley Online Libraryhttps://nph.onlinelibrary.wiley.com/doi/abs/10.1111/nph.14900 Evaluation of proteomic strategies for analyzing ubiquitinated proteins JM Peng - BMB reports, 2008 - koreascience.krhttps://koreascience.kr/article/JAKO200809137570088.page Identification of ubiquitinated proteins from human multiple myeloma U266 cells by proteomics JIA HongLing, LIU ChaoWu, GE Feng - Biomedical and , 2011 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0895398811600871 MaxQuant. Live enables enhanced selectivity and identification of peptides modified by endogenous SUMO and ubiquitin IA Hendriks , V Akimov, B Blagoev - Journal of proteome , 2021 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.jproteome.0c00892 How cargo identity alters the uptake of cell-penetrating peptide (CPP)/Cargo complexes: A study on the effect of net cargo charge and length HC Hymel, A Rahnama , OM Sanchez, D Liu - Cells, 2022 - mdpi.comhttps://www.mdpi.com/2073-4409/11/7/1195 A proteomics approach to identify the ubiquitinated proteins in mouse heart HB Jeon, ES Choi, JH Yoon , JH Hwang - Biochemical and , 2007 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0006291X07007061 A bimolecular affinity purification method under denaturing conditions for rapid isolation of a ubiquitinated protein for mass spectrometry analysis GN Maine, H Li, IW Zaidi, V Basrur - nature protocols, 2010 - nature.comhttps://www.nature.com/articles/nprot.2010.109 Plasmodium falciparum OTU-like cysteine protease (PfOTU) is essential for apicoplast homeostasis and associates with noncanonical role of Atg8 G Datta , ME Hossain, M Asad, S Rathore - Cellular , 2017 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/cmi.12748 Differential Proteomic Screen To Evidence Proteins Ubiquitinated upon Mitotic Exit in Cell-Free Extract of Xenopus laevis Embryos F Bazile, JP Gagne , G Mercier, KS Lo - Journal of Proteome , 2008 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/pr800250x The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination E Karousou , M Kamiryo, SS Skandalis - Journal of Biological , 2010 - ASBMBhttps://www.jbc.org/article/S0021-9258(20)61830-0/abstract Mass spectrometric determination of protein ubiquitination CE Parker, V Mocanu, MR Warren, SF Greer - Ubiquitin-Proteasome , 2005 - Springerhttps://link.springer.com/protocol/10.1385/1-59259-895-1:153 Mass spectrometric determination of protein ubiquitination CE Parker, MW Hines, V Mocanu, SF Greer - The Protein Protocols , 2009 - Springerhttps://link.springer.com/protocol/10.1007/978-1-59745-198-7_157 Mass spectrometric determination of protein ubiquitination CE Parker, MRE Warren Hines, V Mocanu - Modification of Proteins , 2019 - Springerhttps://link.springer.com/protocol/10.1007/978-1-4939-9055-9_13 A method for simple identification of signature peptides derived from polyUb-K48 and K63 by MALDI-TOF MS and chemically assisted MS/MS fragmentation AP Doskeland - Amino acids, 2006 - Springerhttps://link.springer.com/article/10.1007/s00726-005-0227-4

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