400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
| 编号: | 577523 |
| 中文名称: | Bz-RHd-CMK |
| CAS号: | 468102-94-5 |
| 单字母: | Bz-RHd-CMK |
| 三字母: | Benzoyl 苯甲酰基（Bz，C6H5CO-）是醇的芳酰基保护基团，在稀碱性溶液中可通过水解轻易去除。 -ArgL-精氨酸：arginine。系统命名为(2S)-氨基-5-胍基戊酸。在生理条件下带正电荷，为编码氨基酸。是幼小哺乳动物的必需氨基酸。符号：R，Arg。 -HisL-组氨酸：histidine。系统命名为(2S)-氨基-3-(4-咪唑基)丙酸。其侧链带有弱碱性的咪唑基，为编码氨基酸。是幼小哺乳动物的必需氨基酸。符号：H，His。 -DAspD型天冬氨酸 -CMKC端氯甲基酮修饰，Chloromethylketone (CMK) |
| 氨基酸个数: | 3 |
| 分子式: | C24H31O6N8Cl1 |
| 平均分子量: | 563.01 |
| 精确分子量: | 562.21 |
| 等电点(PI): | 9.51 |
| pH=7.0时的净电荷数: | 0.24 |
| 平均亲水性: | 1.8333333333333 |
| 疏水性值: | -3.73 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95% 或98%可选 |
| 盐体系: | 若定制，可选TFA盐、醋酸盐、盐酸盐和柠檬酸盐等 |
| 生成周期: | 现货或定制2-3周，请咨询销售人员 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | D型氨基酸肽 CMK(氯甲基酮)修饰 三肽 |
Bz-Arg-His-D-Asp-CH2Cl is a research tool that can be used as an activator or ligand in cell biology and pharmacology. This product is also a receptor, which is a protein that binds to one or more specific substances (ligands) and triggers a change in the activity of cells. Receptors are often located on the surface of cells, such as those in the brain, heart and muscles. Bz-Arg-His-D-Asp-CH2Cl can be used to inhibit ion channels and has been shown to block receptors for acetylcholine, histamine and serotonin. Bz-Arg-His-D-Asp-CH2Cl also blocks calcium channels and potassium channels. This product has been shown to inhibit the activity of phospholipase A2, which helps break down fats into fatty acids. It also inhibits the activity of aminopeptidases, which breaks down proteins into
很多蛋白在细胞中非常容易被降解，或被标记，进而被选择性地破坏。但含有部分D型氨基酸的多肽则显示了很强的抵抗蛋白酶降解能力。
