400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
溶酶体二肽 LLME 对 NK 细胞、CTL 和 Mphi 具有选择性毒性，而对各种其他淋巴样或非淋巴样细胞类型没有不利影响。
编号：200193
CAS号：16689-14-8
单字母：H2N-LL-OMe
| 编号: | 200193 |
| 中文名称: | 二肽Leu-Leu-甲酯化 |
| CAS号: | 16689-14-8，HBr盐 |
| 单字母: | H2N-LL-OMe |
| 三字母: | H2N N端氨基：N-terminal amino group。在肽或多肽链中含有游离a-氨基的氨基酸一端。在表示氨基酸序列时，通常将N端放在肽链的左边。 -LeuL-亮氨酸：leucine。系统命名为(2S)-氨基-4-甲基戊酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：L，Leu。 -LeuL-亮氨酸：leucine。系统命名为(2S)-氨基-4-甲基戊酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：L，Leu。 -OMeC端甲酯化修饰，甲酯是最简单的酯类，在溶液合成中作为重要的半永久性C端保护基团。它们可以转化为肽肼，而肽肼是反应性肽叠氮化物的先驱体。叠氮偶联仍是肽溶液合成中片段偶联最常用的方法。 |
| 氨基酸个数: | 2 |
| 分子式: | C13H26N2O3 |
| 平均分子量: | 258.36 |
| 精确分子量: | 258.19 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 0.97 |
| 平均亲水性: | -1.8 |
| 疏水性值: | 3.8 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 600+种二肽(Dipeptide)现货 |
The lysosomotropic dipeptide LLME has selective toxicity for NK cells, CTL, and M phi without adverse effects on a variety of other lymphoid or nonlymphoid cell types.
| DOI | 名称 | |
|---|---|---|
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| 10.1073/pnas.82.8.2468 | Regulation of cellular function by products of lysosomal enzyme activity: elimination of human natural killer cells by a dipeptide methyl ester generated from L-leucine methyl ester by monocytes or polymorphonuclear leukocytes | 下载 |
| 10.1021/tx300114x | Lysosomes as a possible target of enniatin B-induced toxicity in Caco-2 cells | 下载 |
