TSST-1 是一种“超抗原”，可与 MHC II 类分子结合并诱导 T 细胞刺激。该 TSST-1 片段具有 TSST-1 全毒素的活性位点，该位点与 MHC II 类分子结合，并能够以 MHC 不受限制的方式异种刺激 T 细胞。因此，该肽对于研究 MHC II 类分子的免疫生物学具有重要价值。
编号：200387
CAS号：137593-46-5
单字母：H2N-KGEKVDLNTKRTKKSQHTSEG-OH
TSST-1 is a "superantigen" which binds to MHC class II molecules and induces stimulation of T cells. This TSST-1 fragment has an active site of the TSST-1 holotoxin which binds to MHC class II molecules and is able to xenostimulate T cells in an MHC unrestricted manner. Therefore this peptide could be of great value in studying the immunobiology of MHC class II molecules.
| DOI | 名称 | |
|---|---|---|
| 10.3109/08820139409066835 | A 21-mer synthetic peptide of toxic shock syndrome toxin 1, TSST-1[58-78], activates T cells by binding to MHC class II and by an MHC unrestricted xenostimulatory pathway | 下载 |
