7535-72-0_二肽Z-Gly-Leu-NH2_Cbz-Gly-Leu-CONH2_Z-GL-CONH2_CBZ修饰肽_ 600+种二肽(Dipeptide)现货

二肽Z-Gly-Leu-NH2
中性金属内切蛋白酶的底物。

编号：200429

CAS号：7535-72-0

单字母：Z-GL-CONH2

编号:	200429
中文名称:	二肽Z-Gly-Leu-NH2
CAS号:	7535-72-0
单字母:	Z-GL-CONH2
三字母:	Cbz N端Cbz保护，苄氧羰基（Cbz，Z） -Gly 甘氨酸：glycine。系统命名为 2-氨基乙酸。是编码氨基酸中没有旋光性的最简单的氨基酸，因具有甜味而得名。符号：G，Gly。 -Leu L-亮氨酸：leucine。系统命名为(2S)-氨基-4-甲基戊酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：L，Leu。 -CONH2 C端酰胺化
氨基酸个数:	2
分子式:	C₁₆H₂₃O₄N₃
平均分子量:	321.37
精确分子量:	321.17
等电点(PI):	-
pH=7.0时的净电荷数:	-
平均亲水性:	-1.8
疏水性值:	1.7
消光系数:	-
来源:	人工化学合成，仅限科学研究使用，不得用于人体。
储存条件:	负80℃至负20℃
标签:	CBZ修饰肽 600+种二肽(Dipeptide)现货

Substrate for neutral metalloendoproteases. Z-GL-amide blocks the exocytotic release of histamine and of catecholamines as well as myoblast fusion. Furthermore, it interferes with insulin processing by adipocytes.

Z-Gly-Leu-NH2 is a peptide that has been shown to have specificities against the bacteria Staphylococcus. It was obtained by the synthesis of a synthetic peptide with a sequence corresponding to the amino acid sequence of casein, which is a protein found in milk. The peptide contains four amino acids and has been shown to induce cytopathic effect in staphylococci, which are rod-shaped bacteria. This peptide also has high thermostability, which means it can be heated up to 100°C for 10 minutes without changing its activity. Z-Gly-Leu-NH2 is stable at pH 5 and is resistant to proteolytic degradation by subtilisin, making it an ideal candidate for use as a food additive.

DOI	名称
10.1016/0092-8674(85)90213-2	Requirement for metalloendoprotease in exocytosis: evidence in mast cells and adrenal chromaffin cells	下载
10.1007/BF01116868	Bilayer stabilizing peptides and the inhibition of viral infection: antimeasles activity of carbobenzoxy-Ser-Leu-amide	下载
10.1073/pnas.83.21.8029	Metalloendoprotease inhibitors that block fusion also prevent biochemical differentiation in L6 myoblasts	下载
10.1016/0006-291x(87)90472-4	Effects of metalloendoprotease inhibitors on insulin binding, internalization and processing in adipocytes	下载
10.1248/cpb.33.1544	Affinity chromatography of neutral metalloendopeptidase produced by Streptomyces mauvecolor on N-benzyloxycarbonylglycyl-D-leucylaminohexyl-Sepharose	下载