1170-76-9_Z-Gly-Phe-OH_Cbz-Gly-Phe-OH_Z-GF-OH_CBZ修饰肽_ 600+种二肽(Dipeptide)现货

Z-Gly-Phe-OH

编号：200431

CAS号：1170-76-9

单字母：Z-GF-OH

编号:	200431
中文名称:	Z-Gly-Phe-OH
中文同义词:	(S)-2-(2-(((苄氧基)羰基)氨基)乙酰氨基)-3-苯基丙酸
英文名:	Z-Gly-Phe-OH
英文同义词:	(S)-2-(2-(((Benzyloxy)carbonyl)amino)acetamido)-3-phenylpropanoic acid
CAS号:	1170-76-9
单字母:	Z-GF-OH
三字母:	Cbz N端Cbz保护，苄氧羰基（Cbz，Z） -Gly 甘氨酸：glycine。系统命名为 2-氨基乙酸。是编码氨基酸中没有旋光性的最简单的氨基酸，因具有甜味而得名。符号：G，Gly。 -Phe L-苯丙氨酸：phenylalanine。系统命名为(2S)-氨基-3-苯基丙酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：F，Phe。 -OH C端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。
氨基酸个数:	2
分子式:	C₁₉H₂₀O₅N₂
平均分子量:	356.37
精确分子量:	356.14
等电点(PI):	-
pH=7.0时的净电荷数:	-
平均亲水性:	-2.5
疏水性值:	1.2
消光系数:	-
来源:	人工化学合成，仅限科学研究使用，不得用于人体。
储存条件:	负80℃至负20℃
标签:	CBZ修饰肽 600+种二肽(Dipeptide)现货

MDL号:

MFCD00037264

Z-Gly-Phe is a peptide that inhibits protein synthesis by binding to the reactive site of a pancreatic enzyme. This site is normally occupied by a hydrogen bond and the compound binds to it by occupying this space, resulting in the inhibition of enzyme activity. Z-Gly-Phe has been shown to inhibit insulin-stimulated glucose uptake in rats, which may be due to its ability to bind with sodium carbonate. The binding constants of Z-Gly-Phe and its inhibitors have been determined using an analytical method that measures changes in pH. The optimum pH for Z-Gly-Phe is 8.5, which corresponds with the optimal pH for human pancreatic enzymes.

DOI	名称
10.1046/j.1432-1033.2003.03681.x	Procarboxypeptidase A from the insect pest Helicoverpa armigera and its derived enzyme. Two forms with new functional properties	下载
10.1021/jm00347a012	Lysosomotropic agents. 4. Carbobenzoxyglycylphenylalanyl, a new protease-sensitive masking group for introduction into cells	下载
10.1111/j.1432-1033.1981.tb06349.x	Crystallization and properties of carboxypeptidase A gamma from porcine pancreas	下载