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来源于组蛋白 H3 1-21 氨基酸,通常用作甲基转移酶 (k4 和 K9) 和乙酰基转移酶 (k9 和K14) 分析的底物。
编号:200725
CAS号:873215-29-3
单字母:H2N-ARTKQTARKSTGGKAPRKQLA-OH
Histone H3 (1-21) 来源于组蛋白 H3 1-21 氨基酸,通常用作甲基转移酶 (k4 和 K9) 和乙酰基转移酶 (k9 和K14) 分析的底物。
Histone H3 (1-21), derived from Histone H3 1-21 amino acids, is usually used as a substrate for methyltransferase (Histone 3 K4 and K9) and acetyltransferase (Histone 3 K9 and K14) assays[1].
Peptide H-ARTKQTARKSTGGKAPRKQLA-OH is a Research Peptide with significant interest within the field academic and medical research. Recent citations using H-ARTKQTARKSTGGKAPRKQLA-OH include the following: The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B Y Zhang , H Yang , X Guo, N Rong, Y Song, Y Xu - Protein & , 2014 - academic.oup.comhttps://academic.oup.com/proteincell/article-abstract/5/11/837/6831772 Selective sensing of phosphorylated peptides and monitoring kinase and phosphatase activity with a supramolecular tandem assay Y Liu , J Lee, L Perez , AD Gill , RJ Hooley - Journal of the , 2018 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/jacs.8b08693 Inhibition of KDM5B participates in immune microenvironment remodeling in pancreatic cancer by inducing STING expression X Li, J Li, Y Liu, L Sun, Q Tai, S Gao, W Jiang - Cytokine, 2024 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1043466623003290 Selenium-Based S-Adenosylmethionine Analog Reveals the Mammalian Seven-Beta-Strand Methyltransferase METTL10 to Be an EF1A1 Lysine Methyltransferase T Shimazu, J Barjau , Y Sohtome , M Sodeoka - PloS one, 2014 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105394 Histone monoaminylation dynamics are regulated by a single enzyme and promote neural rhythmicity Q Zheng , RM Bastle , S Zhao, L Kong, L Vostal - bioRxiv, 2022 - biorxiv.orghttps://www.biorxiv.org/content/10.1101/2022.12.06.519310.abstract HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation MJ Suskiewicz , F Zobel, TEH Ogden, P Fontana - Nature, 2020 - nature.comhttps://www.nature.com/articles/s41586-020-2013-6 Dissecting the Kinetic Mechanism of Human Lysine Methyltransferase 2D and Its Interactions with the WRAD2 Complex LV Edwardes, SJ Caswell, M Giurrandino, X Zhai - Biochemistry, 2022 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.biochem.2c00385 Bioorthogonal Profiling of Protein Methylation (BPPM) Using an Azido Analog of S-Adenosyl-L-Methionine G Blum, K Islam, M Luo - Current protocols in chemical biology, 2013 - Wiley Online Libraryhttps://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/9780470559277.ch120240
Gauthier N, et al. Development of homogeneous nonradioactive methyltransferase and demethylase assays targeting histone H3 lysine 4. J Biomol Screen. 2012;17(1):49-58. : https://pubmed.ncbi.nlm.nih.gov/21940714/