九聚精氨酸是最有效的蛋白质转导结构域之一,也是一种细胞穿透肽。阳性电荷序列。
编号:198599
CAS号:2283335-13-5/143413-47-2
单字母:H2N-RRRRRRRRR-OH
(Arg)9 TFA (Nona-L-arginine TFA)是可渗透细胞的多肽,在谷氨酸模型实验模型中保护神经的IC50值为0.78 μM。
(Arg)9 TFA (Nona-L-arginine TFA), a cell-penetrating peptide, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.
Nonaarginine是最有效的蛋白质转导结构域之一,也是一种细胞穿透肽。
Nonaarginine is one of the most efficient protein transduction domains and a cell-penetrating peptide.
DOI | 名称 | |
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10.1007/s10571-013-9999-3 | The neuroprotective efficacy of cell-penetrating peptides TAT, penetratin, Arg-9, and Pep-1 in glutamic acid, kainic acid, and in vitro ischemia injury models using primary cortical neuronal cultures | 下载 |
10.1038/jcbfm.2015.11 | Poly-arginine and arginine-rich peptides are neuroprotective in stroke models | 下载 |
10.1186/s12868-016-0253-z | Poly-arginine peptides reduce infarct volume in a permanent middle cerebral artery rat stroke model | 下载 |
10.1074/jbc.M209548200 | Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake | 下载 |
10.1002/cbic.200600209 | A targeted protease substrate for a quantitative determination of protease activities in the endolysosomal pathway | 下载 |