3106-85-2_二肽Ac-Asp-Glu_Ac-Asp-Glu-OH_Ac-DE-OH_600+种二肽(Dipeptide)现货

二肽Ac-Asp-Glu
一种对脑谷氨酸受体具有高亲和力的内源性二肽。NAAG 是哺乳动物中枢神经系统中含量最丰富的肽类神经递质。

编号：178689

CAS号：3106-85-2

单字母：Ac-DE-OH

编号:	178689
中文名称:	二肽Ac-Asp-Glu
英文名:	Ac-Asp-Glu
CAS号:	3106-85-2
单字母:	Ac-DE-OH
三字母:	Ac N端乙酰化封端，一种常见的修饰方式，常用于模拟蛋白质中的肽片段。 -Asp L-天冬氨酸：aspartic acid。系统命名为(2S)-氨基-丁二酸。是编码氨基酸，又是神经递质。符号：D，Asp。D-天冬氨酸存在于多种细菌的细胞壁和短杆菌肽A中。 -Glu L-谷氨酸：glutamic acid。系统命名为(2S)-氨基-戊二酸。是编码氨基酸。符号：E，Glu。D-谷氨酸存在于多种细菌的细胞壁和某些细菌杆菌肽中。 -OH C端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。
氨基酸个数:	2
分子式:	C₁₁H₁₆O₈N₂
平均分子量:	304.25
精确分子量:	304.09
等电点(PI):	-
pH=7.0时的净电荷数:	-2
平均亲水性:	3
疏水性值:	-3.5
外观与性状:	白色粉末状固体
消光系数:	-
来源:	人工化学合成，仅限科学研究使用，不得用于人体。
纯度:	95%、98%
盐体系:	可选TFA、HAc、HCl或其它
生成周期:	2-3周
储存条件:	负80℃至负20℃
标签:	600+种二肽(Dipeptide)现货

An endogenous dipeptide with high affinity for a brain glutamate receptor. NAAG is the most abundant peptide neurotransmitter in the mammalian central nervous system.

Ac-Asp-Glu • H2O is a water soluble molecule that belongs to the class of inhibitors. It has been shown to inhibit the polymerase chain reaction and is used as an analytical method for detecting DNA sequences. Ac-Asp-Glu • H2O induces neuronal death in the caudate putamen, thereby causing bowel disease, by inhibiting energy metabolism. This compound also inhibits the synthesis of proteins in the hippocampus, which leads to reduced locomotor activity and eosinophil cationic protein production. Ac-Asp-Glu • H2O is acidic and its concentration–time curve shows a bell shape. The half life of this compound is six hours.

DOI	名称
10.1016/s0003-2697(02)00286-5	Kinetics and inhibition of glutamate carboxypeptidase II using a microplate assay	下载
10.1016/0014-2999(84)90590-9	Characterization of the interactions of N-acetyl-aspartyl-glutamate with [3H]L-glutamate receptors	下载
10.1073/pnas.80.4.1116	N-acetylaspartylglutamate: an endogenous peptide with high affinity for a brain "glutamate" receptor	下载
10.1021/jm950801q	Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated alpha-linked acidic dipeptidase	下载