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对应于鼠层粘连蛋白 α1 链 (2722-2729) C 端球状结构域的片段 LQVQLSIR 代表 AG-73(一种活性细胞粘附肽)的最小活性序列。LQVQLSIR 可能是层粘连蛋白 1 最重要的生物活性位点之一,尤其是在促进恶性表型方面。
编号:156903
CAS号:16364-31-1
单字母:H2N-LE-OH
| 编号: | 156903 |
| 中文名称: | Leu-Glu |
| 英文名: | Leu-Glu |
| CAS号: | 16364-31-1 |
| 单字母: | H2N-LE-OH |
| 三字母: | H2N N端氨基:N-terminal amino group。在肽或多肽链中含有游离a-氨基的氨基酸一端。在表示氨基酸序列时,通常将N端放在肽链的左边。 -LeuL-亮氨酸:leucine。系统命名为(2S)-氨基-4-甲基戊酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号:L,Leu。 -GluL-谷氨酸:glutamic acid。系统命名为(2S)-氨基-戊二酸。是编码氨基酸。符号:E,Glu。D-谷氨酸存在于多种细菌的细胞壁和某些细菌杆菌肽中。 -OHC端羧基:C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时,通常将C端放在肽链的右边。 |
| 氨基酸个数: | 2 |
| 分子式: | C11H20N2O5 |
| 平均分子量: | 260.29 |
| 精确分子量: | 260.14 |
| 等电点(PI): | 6.36 |
| pH=7.0时的净电荷数: | -0.02 |
| 平均亲水性: | 0.6 |
| 疏水性值: | 0.15 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | - |
| 来源: | 人工化学合成,仅限科学研究使用,不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 600+种二肽(Dipeptide)现货 |
The fragment LQVQLSIR corresponding to the C-terminal globular domain of the murine laminin α1 chain (2722-2729) represents the minimal active sequence of AG-73, an active cell-adhesion peptide. LQVQLSIR could be one of the most important biologically active sites of laminin-1, especially in promotion of the malignant phenotype.
24-Epibrassinolide is a synthetic molecule that has an optical rotation of +19.4° at 20°C. It is also known as H-Leu-Glu-OH and is a product of the reaction between epibatidine and L-glutamic acid. This molecule has been synthesized to study the role of 24-epibrassinolide in photosynthesis, chlorophyll synthesis, and membrane stability. The phosphate group is attached to the amino group on the n-terminal amino acid. 24-Epibrassinolide has an amino acid composition consisting of leucine, glutamate, glutamine, glycine, proline, serine, cysteine, tyrosine, asparagine, histidine and lysine.\n24-Epibrassinolide was first isolated from chloroplasts using refluxing water with ammonium chloride as a solvent. This molecule can be found in nature as well.
| DOI | 名称 | |
|---|---|---|
| 10.1021/ac071241t | MS/MS simplification by 355 nm ultraviolet photodissociation of chromophore-derivatized peptides in a quadrupole ion trap | 下载 |
| 10.1016/j.jasms.2008.10.016 | Improved infrared multiphoton dissociation of peptides through N-terminal phosphonite derivatization | 下载 |
| 10.1016/j.ab.2009.11.020 | Role of arginine in chemical cross-linking with N-hydroxysuccinimide esters | 下载 |
| 10.1007/s13361-010-0016-5 | Ultraviolet photodissociation of carboxylate-derivatized peptides in a quadrupole ion trap | 下载 |
| 10.1002/(sici)1097-0215(19980812)77:4<632::aid-ijc25>3.0.co;2-6 | Laminin-alpha1-chain sequence Leu-Gln-Val-Gln-Leu-Ser-Ile-Arg (LQVQLSIR) enhances murine melanoma cell metastases | 下载 |





