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视紫红质肽的化学式为C51H88N14O20，氨基酸序列为H2N-Val-Ser-Lys-Thr-Glu-Thr-Ser-Gln-Val-Ala-Pro-Ala-OH，分子量为1217.33。视紫红质也被称为视觉紫色，是视网膜感光细胞的生物色素，它负责对光线感知的第一步。视紫红质属于G-蛋白偶联受体家族，对光极为敏感(1)。视紫红质基因突变引起各种视网膜病变，如视网膜色素变性。在一般情况下，引起疾病的蛋白质聚集在包涵体，破坏中间纤维网，并损害细胞降解无功能蛋白质的能力，从而导致感光细胞凋亡(2)。视紫红质的其他突变导致X连锁先天性静止性夜盲，这些突变主要集中在视紫红质的生色结合口袋周围，突变引起受体的组成性激活。研究发现与视紫质相关的其他几个病理状态，包括差的高尔基后转运、失调激活、视杆细胞外段的不稳定和结合的干涉。

Peptide H-VSKTETSQVAPA-OH is a Research Peptide with significant interest within the field academic and medical research. Recent citations using H-VSKTETSQVAPA-OH include the following: Melanopsin signaling and nonvisual ocular photoreception SV Yelamanchili, V Piamonte, SK Nayak - Transduction in the , 2007 - books.google.comhttps://books.google.com/books?hl=en&lr=&id=frEQu0Hc6scC&oi=fnd&pg=PA165&dq=(%22VSKTETSQVAPA%22+OR+%22H-VSKTETSQVAPA-OH%22+OR+%22NH2-Val-Ser-Lys-Thr-Glu-Thr-Ser-Gln-Val-Ala-Pro-Ala-OH%22)+AND+peptide&ots=1aHAFIKqHj&sig=GJR0MqC_a7ntrUQ7pPBQdWpFVBs Cooperativity during multiple phosphorylations catalyzed by rhodopsin kinase: supporting evidence using synthetic phosphopeptides N Pullen, NG Brown, RP Sharma, M Akhtar - Biochemistry, 1993 - ACS Publicationshttps://pubs.acs.org/doi/pdf/10.1021/bi00066a016 Characterization of rhodopsin P23H-induced retinal degeneration in a Xenopus laevis model of retinitis pigmentosa BM Tam, OL Moritz - Investigative ophthalmology & visual , 2006 - iovs.arvojournals.orghttps://iovs.arvojournals.org/article.aspx?articleid=2126677