400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
Z-Phe-Tyr（tBu）-重氮甲基酮是组织蛋白酶L的抑制剂，对组织蛋白酶的选择性高于组织蛋白酶S和组织蛋白酶B。
编号：438220
CAS号：114014-15-2
单字母：Z-F-Y(tBu)-CHN2
| 编号: | 438220 |
| 中文名称: | Z-Phe-Tyr(tBu)-diazomethylketone |
| 英文名: | Z-Phe-Tyr(tBu)-diazomethylketone |
| CAS号: | 114014-15-2 |
| 单字母: | Z-F-Y(tBu)-CHN2 |
| 三字母: | Cbz N端Cbz保护，苄氧羰基（Cbz，Z） -PheL-苯丙氨酸：phenylalanine。系统命名为(2S)-氨基-3-苯基丙酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：F，Phe。 -Tyr(tBu)侧链tBu保护的酪氨酸，叔丁基醚保护基团在Fmoc-SPPS中常用于保护丝氨酸、苏氨酸、酪氨酸和羟脯氨酸的含羟基侧链，并可用强酸如三氟乙酸（TFA）去除。 -diazomethylketone重氮甲基酮修饰 |
| 氨基酸个数: | 2 |
| 分子式: | C31H34O5N4 |
| 平均分子量: | 542.63 |
| 精确分子量: | 542.25 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | - |
| 平均亲水性: | -2.5 |
| 疏水性值: | 2.8 |
| 消光系数: | - |
| 标签: | CBZ修饰肽 600+种二肽(Dipeptide)现货 侧链保护基肽 |
Z-Phe-Tyr（tBu）-重氮甲基酮是组织蛋白酶L的抑制剂，对组织蛋白酶的选择性高于组织蛋白酶S和组织蛋白酶B。
Z-Phe-Tyr(tBu)-diazomethylketone is an inhibitor of cathepsin L with selectivity for cathepsin L over cathepsin S and cathepsin B.
Z-Phe-Tyr(tBu)-diazomethylketone is a compound that is used in the treatment of cancer and HIV. It was developed as an antiviral therapy for HIV, but it has been found to be ineffective against HIV. Z-Phe-Tyr(tBu)-diazomethylketone has been shown to produce attenuating effects on syncytial virus and may be a potential antiviral drug. This compound is not active against regulatory sequences or tissues, but it does inhibit endoproteolytic processing of n6-methyladenosine, which leads to modifications in rna binding.
