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编号:486079
CAS号:1491158-62-3
单字母:Palmiticacid-γGlu(OtBu)-deltaLys(Fmoc)-OH
编号: | 486079 |
中文名称: | Fmoc-Lys-(Pal-Glu-OtBu)-OH |
英文名: | Fmoc-Lys-(Pal-Glu-OtBu)-OH |
CAS号: | 1491158-62-3 |
单字母: | Palmiticacid-γGlu(OtBu)-deltaLys(Fmoc)-OH |
三字母: | Palmitoyl 棕榈酸修饰、Palmitic acid (PAL), hexadecanoic acid -γGlu(OtBu)Glu-OtBu -εLys(Fmoc)deltaLys的α位氨基被Fmoc保护,9-芴甲氧羰基(Fmoc)是伯胺和仲胺的保护基团。在固相肽合成(SPPS)中,它是氨基酸主链的常用保护基,因为它可以很容易地用哌啶去除,而不会干扰树脂和肽之间的酸不稳定连接体。 -OHC端羧基:C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时,通常将C端放在肽链的右边。 |
氨基酸个数: | 2 |
分子式: | C46H69O8N3 |
平均分子量: | 792.06 |
精确分子量: | 791.51 |
等电点(PI): | - |
pH=7.0时的净电荷数: | - |
平均亲水性: | - |
疏水性值: | - |
消光系数: | - |
来源: | 人工化学合成,仅限科学研究使用,不得用于人体。 |
纯度: | 95% 或98%可选 |
盐体系: | 若定制,可选TFA盐、醋酸盐、盐酸盐和柠檬酸盐等 |
生成周期: | 现货或定制2-3周,请咨询销售人员 |
储存条件: | 负80℃至负20℃ |
标签: | 烷基化肽 600+种二肽(Dipeptide)现货 利拉鲁肽中间体 |
This is a building block for peptide synthesis. It is a protected lysine derivative that can be used in the formation of peptides. This functionalized lysine derivative can be deprotected and reacted with other amino acids to form peptides. The protecting group, Fmoc, protects the lysine from unwanted reactions during the synthesis process. The side chain, Palmitoyl-Glu-OtBu, allows for the attachment of other molecules to the lysine side chain.
Fmoc-Lys(palmitoyl-Glu-OtBu)-OH is a racemic, solid-phase, industrial building block for the synthesis of peptides and polypeptides. This product is used in the synthesis of liraglutide (a peptide), which is used to treat type 2 diabetes mellitus. The Fmoc-Lys(palmitoyl-Glu-OtBu)-OH is synthesized by a solid phase process using coupling reactions with an acid labile linker. This product has been shown to be an efficient building block for the synthesis of peptides and polypeptides that have a sequence that can be varied by changing the protecting group on the amino acid.
烷基化肽-说明
专肽生物可提供多肽烷基化修饰,增加多肽一端的疏水性,例如常见的C18,C16,C14,C12,以及C6等,也可根据客户要求,接其他长度的烷基化链。
利拉鲁肽中间体