内皮素(Endothelins)_多肽合成-杭州专肽生物技术有限公司

编号：122468

CAS号：121377-67-1

三字母：H2N-His-Leu-Asp-Ile-Ile-Trp-OH

描 述：发现内皮素C-末端片段HLDIIW在ET-B受体上是完全激动剂，而在ET-A受体上是无活性的或弱活性的。

编号：178999

CAS号：117399-93-6

三字母：H2N-Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-OH(Disulfide Bridge:Cys1-Cys15 & Cys3-Cys11)

描 述：Potent constrictor of rat blood vessels in vitro and an effective pressor agent in vivo. Endothelin-3 (ET-3) has been found in high concentrations in the brain and may regulate important functions in neurons and astrocytes, such as proliferation and devel

编号：185718

CAS号：144602-02-8

三字母：H2N-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH(Disulfide Bridge:Cys1-Cys5)

描 述：IRL1038 inhibits ET-B receptor-mediated contraction of guinea-pig ileal and tracheal smooth muscle without any significant agonist activity, but does not affect the ET-A receptor-mediated contraction of rat aortic smooth muscle.

编号：147759

CAS号：

三字母：Ac-His-Leu-Asp-Ile-Ile-Trp-OH

描 述：ETA/ ETB受体激动剂，血管收缩剂。

编号：130599

CAS号：142569-99-1

三字母：Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH

描 述：ET-1类似物IRL1620是ET-B受体最有效和最特异性的激动剂

编号：139532

CAS号：123562-20-9

三字母：H2N-Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH(Disulfide Bridge:Cys1-Cys15 & Cys3-Cys11)

描 述：Endothelin-2 (ET-2) is produced predominantly within the kidney and intestine. It has no unique physiologic functions as compared with ET-1. ET-2 displays similar selectivity for ETA and ETB receptors.

编号：413210

CAS号：

三字母：H2N-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-OH(Disulfide Bridge:Cys1-Cys15 & Cys3-Cys11)

描 述：Endothelin-1 (1-31) (Human) TFA 是一种有效的血管收缩剂和血压升高剂。Endothelin-1 (1-31) (Human) TFA 来源于 chymase 对大 ET-1 的选择性水解。

编号：143001

CAS号：143037-33-6

三字母：Ac-DTrp-Leu-Asp-Ile-Ile-Trp-OH

描 述：Displays high affinity for the ET-A receptor (IC₅₀ = 0.13 µM) and inhibits the ET-1 stimulated arachidonic acid release in rabbit vascular smooth muscle cells. The hexapeptide binds specifically to the pituitary GnRH receptor exhibiting agonistic ac

编号：174965

CAS号：143113-45-5

三字母：Ac-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH

描 述：BQ2020, a linear analog of ET-1, is a selective agonist for ET-B receptors. BQ3020 should be a valuable tool for the study of ET-B receptor responses and distribution.

编号：164076

CAS号：136553-81-6

三字母：cyclo（Trp-DAsp-Pro-DVal-LeuTrp-DAsp-Pro-DVal-Leu）

描 述：BQ-123是一种有效的内皮素拮抗剂，对ET-A受体亚型具有高选择性。