专肽生物_定制多肽合成服务_多肽合成定制服务_多肽合成厂家_多肽合成公司

Kemptide is a synthetic substrate of the PKA catalytically active subunit (PKAc), and can bind along with ATP to PKAc. It contains 5-Carboxyfluorescein (5-FAM), a widely used green fluorescent tag.

"Peptide 5-FAM-LRRASLG-OH is a Research Peptide with significant interest within the field academic and medical research. Recent citations using 5-FAM-LRRASLG-OH include the following: Sequence-Selective Protection of Peptides from Proteolysis X Li , K Chen, Y Zhao - Angewandte Chemie International , 2021 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/anie.202102148 A broad-spectrum peptide inhibitor of beta-lactamase identified using phage display and peptide arrays W Huang, Z Beharry , Z Zhang, T Palzkill - Protein engineering, 2003 - academic.oup.comhttps://academic.oup.com/peds/article-abstract/16/11/853/1508853 Comparison of the Substrate Specificities of cAMP-Dependent Protein Kinase from Bovine Heart and Ascaris suum Muscle T Treptau, P Piram, PF Cook, PH Rodriguez - 1996 - degruyter.comhttps://www.degruyter.com/document/doi/10.1515/bchm3.1996.377.3.203/html Tandem mass spectrometry investigation of ADP-ribosylated kemptide SM Hengel, SA Shaffer , BL Nunn - Journal of the American , 2011 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1016/j.jasms.2008.10.025 Interaction of Protein Kinase Ac from Ascaris suum with Proteins and Peptides: Comparison with the Mammalian Enzyme S Jung, R Hoffmann , T Treptau, PH Rodriguez - Protein Domains: Their , 1997 - Springerhttps://link.springer.com/chapter/10.1007/978-3-642-60848-3_4 Peptide-binding nanoparticle materials with tailored recognition sites for basic peptides S Fa , Y Zhao - Chemistry of Materials, 2017 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.chemmater.7b03253 Kinetic analysis of cAMP-dependent protein kinase: mutations at histidine 87 affect peptide binding and pH dependence S Cox, SS Taylor - Biochemistry, 1995 - ACS Publicationshttps://pubs.acs.org/doi/pdf/10.1021/bi00049a036 A computational analysis of substrate binding strength by phosphorylase kinase and protein kinase A RI Brinkworth, J Horne , B Kobe - Journal of Molecular , 2002 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/jmr.563 MRI biosensor for protein kinase A encoded by a single synthetic gene RD Airan , A Bar-Shir , G Liu , G Pelled - Magnetic resonance , 2012 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/mrm.24483 Fluram-kemptide-Lys8 non-radioactive assay for protein kinase A NA Araujo , A Guevara, MA Lorenzo , M Calabokis - The Protein , 2016 - Springerhttps://link.springer.com/article/10.1007/s10930-016-9667-9 Structural basis for peptide binding in protein kinase A: role of glutamic acid 203 and tyrosine 204 in the peptide-positioning loop MJ Moore, JA Adams , SS Taylor - Journal of Biological Chemistry, 2003 - ASBMBhttps://www.jbc.org/article/S0021-9258(19)32548-7/abstract Establishment and Optimization of Protein Labeling Based on Rare Earth Metal Chelated Tags MI Wei, W Jing, Y Wan-Tao, CAI Yun - Chinese Journal of , 2010 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1872204009600700 Streptococcus pneumoniae detects and responds to foreign bacterial peptide fragments in its environment LJ Hathaway, P Battig, S Reber - Open , 2014 - royalsocietypublishing.orghttps://royalsocietypublishing.org/doi/abs/10.1098/rsob.130224 Study of the affinity between the protein kinase PKA and peptide substrates derived from kemptide using molecular dynamics simulations and MM/GBSA K Mena-Ulecia , A Vergara-Jaque , H Poblete - PLoS , 2014 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109639 Engineering the C-terminus of firefly luciferase as an indicator of covalent modification of proteins JP Waud, GB Sala-Newby, SB Matthews - et Biophysica Acta (BBA , 1996 - Elsevierhttps://www.sciencedirect.com/science/article/pii/0167483895001999 Cushings syndrome mutant PKAL205R exhibits altered substrate specificity JM Lubner , KL Dodge-Kafka , CR Carlson - FEBS , 2017 - Wiley Online Libraryhttps://febs.onlinelibrary.wiley.com/doi/abs/10.1002/1873-3468.12562 A phenylalanine in peptide substrates provides for selectivity between cGMP-and cAMP-dependent protein kinases. JL Colbran, SH Francis, AB Leach, MK Thomas - Journal of Biological , 1992 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0021925819501314 Copyright zyxwvutsrqponmlkjihg JA ADAMS , S TAYLOR - academia.eduhttps://www.academia.edu/download/47141856/Divalent_metal_ions_influence_catalysis_20160710-24302-nkh004.pdf Nelson A. Araujo, Alberto Guevara, MaracaÂ\xada A. Lorenzo, Maritza Calabokis & J Bubis - academia.eduhttps://www.academia.edu/download/55404331/Araujo_NA__Guevara_A__Lorenzo_M__Calabokis_M__Bubis_J__The_Protein_Journal_2016_version_online.pdf kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide IA Leighton, KN Dalby , F Barry Caudwell - FEBS , 1995 - Wiley Online Libraryhttps://febs.onlinelibrary.wiley.com/doi/abs/10.1016/0014-5793(95)01170-J In situ fabrication of cleavable peptide arrays on polydimethylsiloxane and applications for kinase activity assays HH Chen, YC Hsiao, JR Li, SH Chen - Analytica Chimica Acta, 2015 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0003267015000975 Staurosporine tethered peptide ligands that target cAMP-dependent protein kinase (PKA): optimization and selectivity profiling CD Shomin, SC Meyer, I Ghosh - Bioorganic & medicinal chemistry, 2009 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0968089609007147 Effect of cysteic acid position on the negative ion fragmentation of proteolytic derived peptides BJ Williams, KL Kmiec, WK Russell - Journal of The , 2011 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1007/s13361-010-0009-4 Selection of small peptides, inhibitors of translation B Llano-Sotelo, D Klepacki, AS Mankin - Journal of molecular biology, 2009 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0022283609008018 Single-subunit allostery in the kinetics of peptide phosphorylation by protein kinase A A Kuznetsov, J Jarv - Proceedings of the Estonian Academy of , 2008 - academia.eduhttps://www.academia.edu/download/52383171/Single-subunit_allostery_in_the_kinetics20170330-24316-1yytpsg.pdf Kinetic analysis of inhibition of cAMP-dependent protein kinase catalytic subunit by the peptide-nucleoside conjugate AdcAhxArg6 A Kuznetsov, A Uri , G Raidaru, J Jarv - Bioorganic chemistry, 2004 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0045206804000343"

FAM标记说明:
Carboxyfluorescein (FAM) is fluorophor with an excitation at 492 nm ▉ and emission of 517 nm ▉. Donors like FAM and 5FAM are often paired together with acceptors (CPQ2) for FRET experiments.

FAM标记肽的相关文献:
Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections.
Kwon, Ester J., et al. Advanced Materials 29.35 (2017).

Ultrasensitive tumor-penetrating nanosensors of protease activity.
Kwon, Ester J., Jaideep S. Dudani, and Sangeeta N. Bhatia. Nature Biomedical Engineering 1 (2017): 0054.

Seneca Valley Virus 3C pro Substrate Optimization Yields Efficient Substrates for Use in Peptide-Prodrug Therapy.
Miles, Linde A., et al. PloS One 10.6 (2015): e0129103.

The function of the milk-clotting enzymes bovine and camel chymosin studied by a fluorescence resonance energy transfer assay.
Jensen, Jesper Langholm, et al. Journal of Dairy Science 98.5 (2015): 2853-2860.

A comparison of modular PEG incorporation strategies for stabilization of peptide-siRNA nanocomplexes.
Lo, Justin H., et al. Bioconjugate Chemistry (2016).