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59188-54-4,二肽标记肽Z-Phe-Arg-对硝基苯胺,Cbz-Phe-Arg-pNA,Z-FR-pNA,杭州专肽生物的产品

二肽标记肽Z-Phe-Arg-对硝基苯胺

组织蛋白酶L和木瓜蛋白酶的敏感发色底物。

编号:120904

CAS号:59188-54-4

单字母:Z-FR-pNA

纠错
  • 编号:120904
    中文名称:二肽标记肽Z-Phe-Arg-对硝基苯胺
    英文名:Z-Phe-Arg-pNA
    CAS号:59188-54-4
    单字母:Z-FR-pNA
    三字母:Cbz

    N端Cbz保护

    -Phe

    L-苯丙氨酸:phenylalanine。系统命名为(2S)-氨基-3-苯基丙酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号:F,Phe。

    -Arg

    L-精氨酸:arginine。系统命名为(2S)-氨基-5-胍基戊酸。在生理条件下带正电荷,为编码氨基酸。是幼小哺乳动物的必需氨基酸。符号:R,Arg。

    -pNA

    对硝基苯胺

    氨基酸个数:2
    分子式:C29H33O6N7
    平均分子量:575.62
    精确分子量:575.25
    等电点(PI):-
    pH=7.0时的净电荷数:1
    平均亲水性:0.25
    疏水性值:-0.85
    消光系数:-
    来源:人工化学合成,仅限科学研究使用,不得用于人体。
    盐体系:可选TFA、HAc、HCl或其它
    储存条件:负80℃至负20℃
    标签:pNA修饰肽    CBZ修饰肽    二肽(Dipeptide)   

  • Z-FR-pNA, a sensitive chromogenic substrate for cathepsin L and papain. Z-FR-pNA is also cleaved by falcipain 2. CAS Number (net): 117761-01-0.

  • DOI名称
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    10.1046/j.1432-1033.2003.03368.xProperties of purified gut trypsin from Helicoverpa zea, adapted to proteinase inhibitors下载
    10.1104/pp.102.017293Expression of sea anemone equistatin in potato. Effects of plant proteases on heterologous protein production下载
    10.1111/j.1365-294X.2004.02381.xImpact of oilseed rape expressing the insecticidal serine protease inhibitor, mustard trypsin inhibitor-2 on the beneficial predator Pterostichus madidus下载
    10.1016/j.intimp.2004.12.007Proteinase activity and stability of natural bromelain preparations下载
    10.1021/jm050686bInteraction of papain-like cysteine proteases with dipeptide-derived nitriles下载
    10.1074/jbc.M603776200Structural and functional characterization of Falcipain-2, a hemoglobinase from the malarial parasite Plasmodium falciparum下载
    10.1017/S0031182006001302Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo下载
    10.1111/j.1469-8137.2007.01968.xA multicomponent, elicitor-inducible cystatin complex in tomato, Solanum lycopersicum下载
    10.1016/j.biortech.2007.10.018Purification and kinetics of two novel thermophilic extracellular proteases from Lactobacillus helveticus, from kefir with possible biotechnological interest下载
    10.1523/JNEUROSCI.0716-08.2008Cowhage-evoked itch is mediated by a novel cysteine protease: a ligand of protease-activated receptors下载
    10.1515/BC.2008.153Cytotoxic and peptidase inhibitory activities of selected non-hepatotoxic cyclic peptides from cyanobacteria下载
    10.3390/molecules140103782-Amino- and 2-alkylthio-4H-3,1-benzothiazin-4-ones: synthesis, interconversion and enzyme inhibitory activities下载
    10.3390/molecules140104942-amido-3-(1H-indol-3-yl)-N-substituted-propanamides as a new class of falcipain-2 inhibitors. 1. Design, synthesis, biological evaluation and binding model studies下载
    10.1002/arch.20299Digestive proteolysis organization in two closely related Tenebrionid beetles: red flour beetle (Tribolium castaneum) and confused flour beetle (Tribolium confusum)下载
    10.1016/j.jinsphys.2009.04.016CmCatD, a cathepsin D-like protease has a potential role in insect defense against a phytocystatin下载
    10.1016/0167-4838(91)90232-oPhotometric or fluorometric assay of cathepsin B, L and H and papain using substrates with an aminotrifluoromethylcoumarin leaving group下载
    10.1074/jbc.M109.034793Stefin B interacts with histones and cathepsin L in the nucleus下载
    10.1021/jm101272pStructural optimization of azadipeptide nitriles strongly increases association rates and allows the development of selective cathepsin inhibitors下载
    10.1016/B978-0-12-416039-2.00013-6Oral enzyme therapy for celiac sprue下载
    10.1556/ABiol.63.2012.3.4Antimetabolic effect of phytohemagglutinin to the grain aphid Sitobion avenae fabricius下载
    10.1016/j.ymeth.2013.09.007Natural products with protein tyrosine phosphatase inhibitory activity下载
    10.1017/S0022149X13000692The relative anthelmintic efficacy of plant-derived cysteine proteinases on intestinal nematodes下载
    10.1021/jf502170vEffect of pH and recombinant barley (Hordeum vulgare L.) endoprotease B2 on degradation of proteins in soaked barley下载
    10.1002/pro.5560040922High-affinity binding of two molecules of cysteine proteinases to low-molecular-weight kininogen下载
    10.1016/s0020-7519(99)00169-1A comparative survey of the hydrolytic enzymes of ectoparasitic and free-living mites下载
    10.1021/bi0002378Inactivation of cysteine proteases by (acyloxy)methyl ketones using S'-P' interactions下载
    10.1016/j.peptides.2009.06.017Effects of Manduca sexta allatostatin and an analog on the pea aphid Acyrthosiphon pisum (Hemiptera: Aphididae) and degradation by enzymes from the aphid gut下载
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