编号: | 120904 |
中文名称: | 二肽标记肽Z-Phe-Arg-对硝基苯胺 |
英文名: | Z-Phe-Arg-pNA |
CAS号: | 59188-54-4 |
单字母: | Z-FR-pNA |
三字母: | Cbz N端Cbz保护 -PheL-苯丙氨酸:phenylalanine。系统命名为(2S)-氨基-3-苯基丙酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号:F,Phe。 -ArgL-精氨酸:arginine。系统命名为(2S)-氨基-5-胍基戊酸。在生理条件下带正电荷,为编码氨基酸。是幼小哺乳动物的必需氨基酸。符号:R,Arg。 -pNA对硝基苯胺 |
氨基酸个数: | 2 |
分子式: | C29H33O6N7 |
平均分子量: | 575.62 |
精确分子量: | 575.25 |
等电点(PI): | - |
pH=7.0时的净电荷数: | 1 |
平均亲水性: | 0.25 |
疏水性值: | -0.85 |
消光系数: | - |
来源: | 人工化学合成,仅限科学研究使用,不得用于人体。 |
盐体系: | 可选TFA、HAc、HCl或其它 |
储存条件: | 负80℃至负20℃ |
标签: | pNA修饰肽 CBZ修饰肽 二肽(Dipeptide) |
Z-FR-pNA, a sensitive chromogenic substrate for cathepsin L and papain. Z-FR-pNA is also cleaved by falcipain 2. CAS Number (net): 117761-01-0.
DOI | 名称 | |
---|---|---|
10.1074/jbc.M207162200 | Identification of a novel maturation mechanism and restricted substrate specificity for the SspB cysteine protease of Staphylococcus aureus | 下载 |
10.1046/j.1432-1033.2003.03368.x | Properties of purified gut trypsin from Helicoverpa zea, adapted to proteinase inhibitors | 下载 |
10.1104/pp.102.017293 | Expression of sea anemone equistatin in potato. Effects of plant proteases on heterologous protein production | 下载 |
10.1111/j.1365-294X.2004.02381.x | Impact of oilseed rape expressing the insecticidal serine protease inhibitor, mustard trypsin inhibitor-2 on the beneficial predator Pterostichus madidus | 下载 |
10.1016/j.intimp.2004.12.007 | Proteinase activity and stability of natural bromelain preparations | 下载 |
10.1021/jm050686b | Interaction of papain-like cysteine proteases with dipeptide-derived nitriles | 下载 |
10.1074/jbc.M603776200 | Structural and functional characterization of Falcipain-2, a hemoglobinase from the malarial parasite Plasmodium falciparum | 下载 |
10.1017/S0031182006001302 | Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo | 下载 |
10.1111/j.1469-8137.2007.01968.x | A multicomponent, elicitor-inducible cystatin complex in tomato, Solanum lycopersicum | 下载 |
10.1016/j.biortech.2007.10.018 | Purification and kinetics of two novel thermophilic extracellular proteases from Lactobacillus helveticus, from kefir with possible biotechnological interest | 下载 |
10.1523/JNEUROSCI.0716-08.2008 | Cowhage-evoked itch is mediated by a novel cysteine protease: a ligand of protease-activated receptors | 下载 |
10.1515/BC.2008.153 | Cytotoxic and peptidase inhibitory activities of selected non-hepatotoxic cyclic peptides from cyanobacteria | 下载 |
10.3390/molecules14010378 | 2-Amino- and 2-alkylthio-4H-3,1-benzothiazin-4-ones: synthesis, interconversion and enzyme inhibitory activities | 下载 |
10.3390/molecules14010494 | 2-amido-3-(1H-indol-3-yl)-N-substituted-propanamides as a new class of falcipain-2 inhibitors. 1. Design, synthesis, biological evaluation and binding model studies | 下载 |
10.1002/arch.20299 | Digestive proteolysis organization in two closely related Tenebrionid beetles: red flour beetle (Tribolium castaneum) and confused flour beetle (Tribolium confusum) | 下载 |
10.1016/j.jinsphys.2009.04.016 | CmCatD, a cathepsin D-like protease has a potential role in insect defense against a phytocystatin | 下载 |
10.1016/0167-4838(91)90232-o | Photometric or fluorometric assay of cathepsin B, L and H and papain using substrates with an aminotrifluoromethylcoumarin leaving group | 下载 |
10.1074/jbc.M109.034793 | Stefin B interacts with histones and cathepsin L in the nucleus | 下载 |
10.1021/jm101272p | Structural optimization of azadipeptide nitriles strongly increases association rates and allows the development of selective cathepsin inhibitors | 下载 |
10.1016/B978-0-12-416039-2.00013-6 | Oral enzyme therapy for celiac sprue | 下载 |
10.1556/ABiol.63.2012.3.4 | Antimetabolic effect of phytohemagglutinin to the grain aphid Sitobion avenae fabricius | 下载 |
10.1016/j.ymeth.2013.09.007 | Natural products with protein tyrosine phosphatase inhibitory activity | 下载 |
10.1017/S0022149X13000692 | The relative anthelmintic efficacy of plant-derived cysteine proteinases on intestinal nematodes | 下载 |
10.1021/jf502170v | Effect of pH and recombinant barley (Hordeum vulgare L.) endoprotease B2 on degradation of proteins in soaked barley | 下载 |
10.1002/pro.5560040922 | High-affinity binding of two molecules of cysteine proteinases to low-molecular-weight kininogen | 下载 |
10.1016/s0020-7519(99)00169-1 | A comparative survey of the hydrolytic enzymes of ectoparasitic and free-living mites | 下载 |
10.1021/bi0002378 | Inactivation of cysteine proteases by (acyloxy)methyl ketones using S'-P' interactions | 下载 |
10.1016/j.peptides.2009.06.017 | Effects of Manduca sexta allatostatin and an analog on the pea aphid Acyrthosiphon pisum (Hemiptera: Aphididae) and degradation by enzymes from the aphid gut | 下载 |