400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
| 编号: | 569957 |
| 中文名称: | 5FAM-Leu-Val-Glu-Ala-Leu-Tyr-OH |
| 单字母: | 5FAM-LVEALY-OH |
| 三字母: | 5FAM N端标记5-FAM，5-羧基荧光素（5FAM）是一种荧光染料，其激发波长为492纳米，发射波长为517纳米。在荧光共振能量转移（FRET）实验中，像FAM和5FAM这样的供体通常与受体（CPQ2）配对使用。 -LeuL-亮氨酸：leucine。系统命名为(2S)-氨基-4-甲基戊酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：L，Leu。 -ValL-缬氨酸：valine。系统命名为(2S)-氨基-3-甲基丁酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：V，Val。在某些放线菌素如缬霉素中存在 D-缬氨酸。 -GluL-谷氨酸：glutamic acid。系统命名为(2S)-氨基-戊二酸。是编码氨基酸。符号：E，Glu。D-谷氨酸存在于多种细菌的细胞壁和某些细菌杆菌肽中。 -Ala丙氨酸：alanine。L-丙氨酸的系统命名为(2S)-氨基丙酸，是编码氨基酸，也叫L-α-丙氨酸。符号：A，Ala。D-丙氨酸存在于多种细菌细胞壁的糖肽中。β-丙氨酸是维生素泛酸和辅酶A的组分。 -LeuL-亮氨酸：leucine。系统命名为(2S)-氨基-4-甲基戊酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：L，Leu。 -TyrL-酪氨酸：tyrosine。系统命名为(2S)-氨基-3-(4-羟基苯基)丙酸。是编码氨基酸。符号：Y，Tyr。 -OHC端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。 |
| 氨基酸个数: | 6 |
| 分子式: | C55H64O16N6 |
| 平均分子量: | 1065.13 |
| 精确分子量: | 1064.44 |
| 等电点(PI): | 7.11 |
| pH=7.0时的净电荷数: | - |
| 平均亲水性: | -1 |
| 疏水性值: | 1.53 |
| 消光系数: | 1490 |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95% 或98%可选 |
| 盐体系: | 若定制，可选TFA盐、醋酸盐、盐酸盐和柠檬酸盐等 |
| 生成周期: | 现货或定制2-3周，请咨询销售人员 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | FAM标记肽 |
Peptide 5Fam-LVEALY-OH is a Research Peptide with significant interest within the field academic and medical research. Recent citations using 5Fam-LVEALY-OH include the following: HMG Advance Access published April 16, 2015 SN Fontaine, MD Martin, E Akoury , VA Assimon - Citeseerhttps://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=e9d096785d8b0e41e4447c5c21cb2f257815a7bf The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics SN Fontaine, MD Martin , E Akoury - Human molecular , 2015 - academic.oup.comhttps://academic.oup.com/hmg/article-abstract/24/14/3971/2385773 Biophysical elucidation of amyloid fibrillation inhibition and prevention of secondary nucleation by cholic acid: an unexplored function of cholic acid N Majid , MK Siddiqi , AN Khan - ACS Chemical , 2019 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acschemneuro.9b00482 Cholic acid inhibits amyloid fibrillation: Interplay of protonation and deprotonation N Majid , MK Siddiqi , A Alam , S Malik, W Ali - International Journal of , 2022 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0141813022019419 Elucidating the inhibitory potential of designed peptides against amyloid fibrillation and amyloid associated cytotoxicity MK Siddiqi , P Alam, T Iqbal , N Majid , S Malik - Frontiers in , 2018 - frontiersin.orghttps://www.frontiersin.org/articles/10.3389/fchem.2018.00311/full Both beta sheet breaker and alpha helix forming pentapeptide inhibits protein fibrillation: Implication for the treatment of amyloid disorders MK Siddiqi , N Majid , P Alam, S Malik, A Alam - International journal of , 2020 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0141813019376792 A systematic screen of beta2-microglobulin and insulin for amyloid-like segments MI Ivanova , MJ Thompson - Proceedings of the , 2006 - National Acad Scienceshttps://www.pnas.org/doi/abs/10.1073/pnas.0511298103 Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks M Meister-Broekema, R Freilich , C Jagadeesan - Nature , 2018 - nature.comhttps://www.nature.com/articles/s41467-018-07718-5 Purification and characterization of two extracellular proteases with unusual peptide bond specificity from Xanthomonas campestris pv. malvacearum JL Huang - 1992 - shareok.orghttps://shareok.org/bitstream/handle/11244/13486/Thesis-1992-H874p.pdf?sequence=1 Investigating the effects of amino acid-based surface modification of carbon nanoparticles on the kinetics of insulin amyloid formation HR Kalhor , A Yahyazadeh - Colloids and Surfaces B: Biointerfaces, 2019 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S092777651930030X Alteration of muscle protein degradation and lipid metabolism by an insulin-derived peptide FG HAMEL, J FAWCETT, WC DUCKWORTH - Diabetes, 2000 - go.gale.comhttps://go.gale.com/ps/i.do?id=GALE%7CA62891338&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=00121797&p=AONE&sw=w Exploring Cooperation and Competition in Molecular Chaperone Networks with Chemical Genetics and Peptide Microarrays. A Gillies - 2013 - deepblue.lib.umich.eduhttps://deepblue.lib.umich.edu/handle/2027.42/99901
FAM标记说明:
Carboxyfluorescein (FAM) is fluorophor with an excitation at 492 nm ▉ and emission of 517 nm ▉. Donors like FAM and 5FAM are often paired together with acceptors (CPQ2) for FRET experiments.
FAM标记肽的相关文献:
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Seneca Valley Virus 3C pro Substrate Optimization Yields Efficient Substrates for Use in Peptide-Prodrug Therapy.
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The function of the milk-clotting enzymes bovine and camel chymosin studied by a fluorescence resonance energy transfer assay.
Jensen, Jesper Langholm, et al. Journal of Dairy Science 98.5 (2015): 2853-2860.
A comparison of modular PEG incorporation strategies for stabilization of peptide-siRNA nanocomplexes.
Lo, Justin H., et al. Bioconjugate Chemistry (2016).
