专肽生物_定制多肽合成服务_多肽合成定制服务_多肽合成厂家_多肽合成公司

Neuropeptide S (human)作为同源神经肽 S 受体 (NPSR) 激动剂。

Neuropeptide S human 是有效的内源性 neuropeptide S receptor 激动剂 (EC50=9.4 nM)。Neuropeptide S human (TFA) 可提高小鼠的运动活性和清醒性。Neuropeptide S human 有潜力用于阿尔茨海默症 (AD) 的研究。

Neuropeptide S human is a potent endogenous neuropeptide S receptor agonist (EC50=9.4 nM). Neuropeptide S human increases locomotor activity and wakefulness in mice. Neuropeptide S human (TFA) has the potential for Alzheimer's disease (AD) treatment.

一种在唤醒和恐惧反应中起作用的神经肽。

A neuropeptide that plays a role in arousal and fear responses.

"Peptide H-SFRNGVGTGMKKTSFQRAKS-OH is a Research Peptide with significant interest within the field academic and medical research. Recent citations using H-SFRNGVGTGMKKTSFQRAKS-OH include the following: Structure-activity study at positions 3 and 4 of human neuropeptide S V Camarda, C Trapella , R Guerrini, A Rizzi - Bioorganic & medicinal , 2008 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S096808960800816X Synthesis and biological activity of human neuropeptide S analogues modified in position 2 V Camarda, C Trapella , G Calo - Journal of medicinal , 2008 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/jm701204n In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1 V Camarda, C Ruzza , A Rizzi, C Trapella , R Guerrini - Peptides, 2013 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0196978113002581 Molecular evolution of the neuropeptide S receptor T Pitti, N Manoj - PLoS One, 2012 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0034046 Specific detection of serum antibodies against BKPyV, a small DNA tumour virus, in patients affected by choroidal nevi S Pietrobon, I Bononi , F Lotito, P Perri - Frontiers in , 2017 - frontiersin.orghttps://www.frontiersin.org/articles/10.3389/fmicb.2017.02059/full Structure-Activity Relationship of Imidazopyridinium Analogues as Antagonists of Neuropeptide S Receptor S Patnaik, JJ Marugan, K Liu, W Zheng - Journal of medicinal , 2013 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/jm400904m Neurobiology, pharmacology, and medicinal chemistry of neuropeptide S and its receptor R Guerrini, S Salvadori, A Rizzi - Medicinal research , 2010 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/med.20180 Neutralizing and IgG antibodies against simian virus 40 in healthy pregnant women in Italy M Comar, C Wong, M Tognon , JS Butel - PLoS One, 2014 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110700 Elucidation of signaling properties of vasopressin receptor-related receptor 1 by using the chimeric receptor approach J Gupte, G Cutler , JL Chen - Proceedings of the , 2004 - National Acad Scienceshttps://www.pnas.org/doi/abs/10.1073/pnas.0308250100 Neurological Disease-Affected Patients, including Multiple Sclerosis, Are Poor Responders to BKPyV, a Human Polyomavirus I Bononi , E Mazzoni , S Pietrobon - Journal of , 2022 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1155/2022/4864950 Synthesis and pharmacological characterization of 5-phenyl-2-2-(1-piperidinylcarbonyl) phenyl-2, 3-dihydro-1H-pyrrolo 1, 2-c imidazol-1-ones: A new class of F Micheli, R Di Fabio, A Giacometti, A Roth - Bioorganic & medicinal , 2010 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0960894X10015283 Significant low prevalence of antibodies reacting with simian virus 40 mimotopes in serum samples from patients affected by inflammatory neurologic diseases E Mazzoni , S Pietrobon, I Masini, JC Rotondo - PLoS , 2014 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110923 Significant Low Prevalence of Antibodies Reacting with Simian Virus 40 Mimotopes E Mazzoni , S Pietrobon, I Masini, JC Rotondo - 2014 - academia.eduhttps://www.academia.edu/download/53635594/Significant_low_prevalence_of_antibodies20170623-2956-15vb84d.pdf Significant prevalence of antibodies reacting with simian virus 40 mimotopes in sera from patients affected by glioblastoma multiforme E Mazzoni , M Gerosa, F Lupidi, A Corallini - Neuro , 2014 - academic.oup.comhttps://academic.oup.com/neuro-oncology/article-abstract/16/4/513/1114202 Serum IgG antibodies from pregnant women reacting to mimotopes of simian virus 40 large T antigen, the viral oncoprotein E Mazzoni , M Di Stefano , JR Fiore , F Destro - Frontiers in , 2017 - frontiersin.orghttps://www.frontiersin.org/articles/10.3389/fimmu.2017.00411/full Sera from patients with malignant pleural mesothelioma tested positive for IgG antibodies against SV40 large t antigen: the viral oncoprotein E Mazzoni , I Bononi , JC Rotondo - Journal of , 2022 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1155/2022/7249912 Antibodies against mimotopes of simian virus 40 large T antigen, the oncoprotein, in serum samples from elderly healthy subjects E Mazzoni , G Guerra, MV Casali - Journal of Cellular , 2017 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.25405 Serologic investigation of undifferentiated nasopharyngeal carcinoma and simian virus 40 infection E Mazzoni , F Martini , A Corallini, A Taronna - Head & , 2016 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/hed.23879 High prevalence of serum antibodies reacting with simian virus 40 capsid protein mimotopes in patients affected by malignant pleural mesothelioma E Mazzoni , A Corallini, A Cristaudo - Proceedings of the , 2012 - National Acad Scienceshttps://www.pnas.org/doi/abs/10.1073/pnas.1213238109 Discovery of sea urchin NGFFFamide receptor unites a bilaterian neuropeptide family DC Semmens, I Beets, ML Rowe - Open , 2015 - royalsocietypublishing.orghttps://royalsocietypublishing.org/doi/abs/10.1098/rsob.150030 Neuropeptide S receptor: recent updates on nonpeptide antagonist discovery D Dal Ben, I Antonini, M Buccioni - , 2011 - Wiley Online Libraryhttps://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cmdc.201100038 tBu-D-Gly5 NPS, a pure and potent antagonist of the neuropeptide S receptor: in vitro and in vivo studies C Ruzza , A Rizzi, V Camarda, A Pulga, G Marzola - Peptides, 2012 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0196978112000605 Structure-activity studies on neuropeptide S: identification of the amino acid residues crucial for receptor activation AL Roth, E Marzola, A Rizzi, M Arduin - Journal of biological , 2006 - ASBMBhttps://www.jbc.org/article/S0021-9258(18)95209-9/abstract Characterization of NGFFYamide signaling in starfish reveals roles in regulation of feeding behavior and locomotory systems AB Tinoco , DC Semmens, EC Patching - Frontiers in , 2018 - frontiersin.orghttps://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2018.00507 Serological evidence of an early seroconversion to Simian virus 40 in healthy children and adolescents A Taronna, E Mazzoni , A Corallini, I Bononi - PloS one, 2013 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0061182 Peptides and proteins in a confined environment: NMR spectra at natural isotopic abundance A Pastore, S Salvadori - of the European Peptide , 2007 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/psc.848 Specific antibodies reacting with simian virus 40 capsid protein mimotopes in serum samples from healthy blood donors A Corallini, E Mazzoni , A Taronna, M Manfrini - Human immunology, 2012 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0198885912000444"

Neuropeptide S is a neuropeptide and a novel modulator of arousal and anxiety. This neuropeptide is found in the mammalian brain and is also involved in the suppression of food intake, reward-like effects, mediation of fear expression and memory and learning processes. This product can be used in pharmacological research and is available as a 0.5 mg vial.

Xu YL, et al. Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects.Neuron. 2004 Aug 19;43(4):487-97. : https://pubmed.ncbi.nlm.nih.gov/15312648/