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VPM peptide TFA 是一种二硫醇蛋白酶可裂解的肽交联剂。VPM peptide TFA 可掺入到 PEG-diacrylate (PEG-DA) 大分子单体的主链中以形成 PEG 水凝胶。

VPM peptide TFA is a dithiol protease-cleavable peptide cross-linker. VPM peptide TFA can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel.

Peptide H-GCRDVPMSMRGGDRCG-OH is a Research Peptide with significant interest within the field academic and medical research. Recent citations using H-GCRDVPMSMRGGDRCG-OH include the following: Light-triggered in vivo activation of adhesive peptides regulates cell adhesion, inflammation and vascularization of biomaterials Z Shafiq , A Shekaran, A del Campo , AJ GarcacaÂ\xada - 2014 - academia.eduhttps://www.academia.edu/download/85354223/nmat415720220502-1-9bb16m.pdf Synthetic matrix enhances transplanted satellite cell engraftment in dystrophic and aged skeletal muscle with comorbid trauma WM Han , SE Anderson, M Mohiuddin , D Barros - Science , 2018 - science.orghttps://www.science.org/doi/abs/10.1126/sciadv.aar4008 Bone regeneration using MMP-cleavable peptides-based hydrogels W Chen, Z Zhou, D Chen, Y Li, Q Zhang , J Su - Gels, 2021 - mdpi.comhttps://www.mdpi.com/2310-2861/7/4/199 Light-triggered in vivo activation of adhesive peptides regulates cell adhesion, inflammation and vascularization of biomaterials TT Lee , JR GarcacaÂ\xada , JI Paez , A Singh , EA Phelps - Nature materials, 2015 - nature.comhttps://www.nature.com/articles/nmat4157 Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes SM Gutowski, JT Shoemaker , KL Templeman, Y Wei - Biomaterials, 2015 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0142961214012538 Engineered Full-Length Fibronectin-Hyaluronic Acid Hydrogels for Stem Cell Engineering S Trujillo , SL Vega , KH Song - Advanced , 2020 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.202000989 Dynamic mechanical control of alginate-fibronectin hydrogels with dual crosslinking: covalent and ionic S Trujillo , M Seow, A Lueckgen, M Salmeron-Sanchez - Polymers, 2021 - mdpi.comhttps://www.mdpi.com/2073-4360/13/3/433 Evaluation of hydrogels presenting extracellular matrix-derived adhesion peptides and encapsulating cardiac progenitor cells for cardiac repair S Bhutani, ALY Nachlas , ME Brown - ACS biomaterials , 2018 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.7b00502 ALLPEPTIDEetic PEG-MAL Hydrogel Stimulates Angiogenic Sprouting in Mouse Aortic Rings R Rath, EAPAJ GarcacaÂ\xada - abstracts.biomaterials.orghttps://abstracts.biomaterials.org/data/papers/2011/465.pdf A hydrogel platform that incorporates laminin isoforms for efficient presentation of growth factors-neural growth and osteogenesis O Dobre , MAG Oliva , G Ciccone - Advanced Functional , 2021 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202010225 Effect of PEG-4MAL Hydrogel Encapsulation Parameters on Dendritic Cells NM Beskid, AJ GarcacaÂ\xada, JE Babensee - abstracts.biomaterials.orghttps://abstracts.biomaterials.org/data/papers/2018/abstracts/812.pdf Engineering PEG-4MAL Hydrogels for Tolerogenic Dendritic Cells NM Beskid, AJ GarcacaÂ\xada, JE Babensee - abstracts.biomaterials.orghttp://abstracts.biomaterials.org/data/papers/2019/abstracts/876.pdf Peptide cross-linked poly (ethylene glycol) hydrogel films as biosensor coatings for the detection of collagenase N Ahmad , B Colak, DW Zhang , MJ Gibbs, M Watkinson - Sensors, 2019 - mdpi.comhttps://www.mdpi.com/1424-8220/19/7/1677 A hydrogel strategy to augment tissue adenosine to improve hindlimb perfusion MN Sayegh , KA Cooney, WM Han , L Wang - , and vascular biology, 2021 - Am Heart Assochttps://www.ahajournals.org/doi/abs/10.1161/ATVBAHA.120.315428 VEGF-delivering PEG hydrogels promote vascularization in the porcine subcutaneous space MJ Quizon, JN Deppen, GF Barber - Research Part A, 2024 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/jbm.a.37666 Extracellular matrix in synthetic hydrogel-based prostate cancer organoids regulate therapeutic response to EZH2 and DRD2 inhibitors MJ Mosquera, S Kim , R Bareja , Z Fang - Advanced , 2022 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/adma.202100096 In situ formed antibacterial hydrogel with collagenase-responsive activity for prevention of MRSA-induced osteomyelitis K Li, X Ju, X Li, G Lu, J Ou, D Xu, C Wan, M Zhu - Chemical Engineering , 2024 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1385894724029620 Enhanced stem cell retention and antioxidative protection with injectable, ROS-degradable PEG hydrogels JR Martin , P Patil , F Yu, MK Gupta , CL Duvall - Biomaterials, 2020 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0142961220306232 Integrin-specific hydrogels functionalized with VEGF for vascularization and bone regeneration of critical-size bone defects JR GarcacaÂ\xada , AY Clark , AJ GarcacaÂ\xada - Journal of biomedical , 2016 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/jbm.a.35626 Synthetic poly (ethylene glycol)-based microfluidic islet encapsulation reduces graft volume for delivery to highly vascularized and retrievable transplant site JD Weaver , DM Headen , MM Coronel - American Journal of , 2019 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1600613522090670 Protease-degradable microgels for protein delivery for vascularization GA Foster , DM Headen , C Gonzalez-GarcacaÂ\xada - Biomaterials, 2017 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0142961216305956 http://eprints. gla. ac. uk/131653 GA Foster , DM Headen , C Gonzalez-GarcacaÂ\xada - academia.eduhttps://www.academia.edu/download/71022150/131653.pdf Maleimide cross-linked bioactive PEG hydrogel exhibits improved reaction kinetics and cross-linking for cell encapsulation and in-situ delivery EA Phelps , MNO Enemchukwu, MVF Fiore - (Deerfield Beach, Fla , 2012 - ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517145/ Engineered VEGF-releasing PEG-MAL hydrogel for pancreatic islet vascularization EA Phelps , KL Templeman, PM Thule - Drug delivery and , 2015 - Springerhttps://link.springer.com/article/10.1007/s13346-013-0142-2 Hydrogel delivery of lysostaphin eliminates orthopedic implant infection by Staphylococcus aureus and supports fracture healing CT Johnson , JA Wroe , R Agarwal - Proceedings of the , 2018 - National Acad Scienceshttps://www.pnas.org/doi/abs/10.1073/pnas.1801013115 Dual delivery of hepatocyte and vascular endothelial growth factors via a protease-degradable hydrogel improves cardiac function in rats AS Salimath , EA Phelps , AV Boopathy , P Che - PloS one, 2012 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050980 Cell-biomaterial interactions: the role of ligand functionalization A Zoso , M Boffito, R Laurano, I Carmagnola - Handbook of , 2020 - Elsevierhttps://www.sciencedirect.com/science/article/pii/B9780081029671000098 Modular immune organoids with integrin ligand specificity differentially regulate ex vivo B cell activation A Purwada, SB Shah , W Beguelin - ACS Biomaterials , 2017 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.6b00474 4D biomaterials for light-guided angiogenesis A Farrukh , JI Paez , A del Campo - Advanced functional , 2019 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.201807734

Phelps EA, et, al. Maleimide cross-linked bioactive PEG hydrogel exhibits improved reaction kinetics and cross-linking for cell encapsulation and in situ delivery. Adv Mater. 2012 Jan 3;24(1):64-70, 2 : https://pubmed.ncbi.nlm.nih.gov/22174081/
Foster GA, et, al. Protease-degradable microgels for protein delivery for vascularization. Biomaterials. 2017 Jan;113:170-175. : https://pubmed.ncbi.nlm.nih.gov/27816000/