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破伤风类毒素的破伤风830修饰/T辅助表位是一种通用的人类破伤风毒素T细胞表位。它诱导T细胞活化,并在疫苗接种中用作辅助肽。
编号:200683
CAS号:410527-75-2
单字母:H2N-AQYIKANSKFIGITEL-OH
| 参考文献(References): | Valmori, D. et al. J. Immunol. 149, 717 (1992) Slingluff, C. Jr. et al. Clin. Cancer Res. 7, 3012 (2001) Slingluff, C. Jr. et al. J. Clin. Oncol. 21, 4016 (2003) Demotz, S. et al. J. Immunol. 142, 394 (1989). |
TET 830 modified/T-helper epitope from tetanus toxoid 是破伤风类毒素的一个修饰T辅助表位。TET 830 modified/T-helper epitope from tetanus toxoid 诱导 T 细胞辅助反应,并作为辅助肽用于疫苗接种。
TET 830 modified/T-helper epitope from tetanus toxoid is a modified T-helper epitope from tetanus toxoid. TET 830 modified/T-helper epitope from tetanus toxoid induces T-cells responses and is used as a helper peptide in vaccinations.
破伤风类毒素的破伤风830修饰/T辅助表位是一种通用的人类破伤风毒素T细胞表位。它诱导T细胞活化,并在疫苗接种中用作辅助肽。
TET 830 modified/T-helper epitope from tetanus toxoid is a universal human tetanus toxin T cell epitope. It induces T-cell activation and is used as a helper peptide in vaccinations.
破伤风毒素 T 细胞表位 TET 830 修饰体包含一段明确的 MHC II 类限制性序列。残基排列优化 T 细胞受体及多肽 - MHC 相互作用。构象可塑性支持免疫识别研究。研究人员将其用于表位定位及疫苗相关结构免疫学研究。
TET 830 modified/T-helper epitope from tetanus toxoid comprises a defined MHC class II–restricted sequence. Residue arrangement optimizes T-cell receptor and peptide–MHC interactions. Conformational plasticity supports immunological recognition studies. Researchers use it in epitope mapping and vaccine-related structural immunology.
Slingluff CL Jr, et al. Phase I trial of a melanoma vaccine with gp100(280-288) peptide and tetanus helper peptide in adjuvant: immunologic and clinical outcomes. Clin Cancer Res. 2001;7(10):3012-3024. : https://pubmed.ncbi.nlm.nih.gov/11595689/





