400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
| 编号: | 206398 |
| 中文名称: | N-芴甲氧羰基-N'-三苯甲基-D-组氨酸/Fmoc-DHis(Trt)-OH |
| 英文名: | Fmoc-D-His(Trt)-OH |
| CAS号: | 135610-90-1 |
| 单字母: | Fmoc-DHis(Trt)-OH |
| 三字母: | Fmoc N端Fmoc保护，9-芴甲氧羰基（Fmoc）是伯胺和仲胺的保护基团。在固相肽合成（SPPS）中，它是氨基酸主链的常用保护基，因为它可以很容易地用哌啶去除，而不会干扰树脂和肽之间的酸不稳定连接体。 -DHis(Trt)侧链Trt保护的D型组氨酸 -OHC端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。 |
| 氨基酸个数: | 1 |
| 分子式: | C40H33O4N3 |
| 平均分子量: | 619.71 |
| 精确分子量: | 619.25 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | - |
| 平均亲水性: | - |
| 疏水性值: | - |
| 外观与性状: | 粉末状固体 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | Fmoc保护氨基酸 |
Fmoc-D-His(Trt)-OH is a chiral building block that is used in peptide synthesis. It can be used to synthesize an enantiomer or homologue of the original amino acid. Fmoc-D-His(Trt)-OH has been postulated to exist as two stereoisomers, 1R,2S and 2R,1S. The 1R,2S enantiomer is the naturally occurring form of this compound and is produced with a shift of +6 ppm in the proton NMR spectrum. The 2R,1S enantiomer has also been observed in the solid state but not in solution and it exhibits a shift of -6 ppm in the proton NMR spectrum.\nFmoc-D-His(Trt)-OH is soluble in solvents such as DMSO and DMF. It has also been shown to be a potent inhibitor of organophosphate and re
