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TAT (YGRKKRRQRRR) 源自人免疫缺陷病毒 (HIV-1) 的转录反式激活因子 (TAT)，是一种穿透细胞的肽。TAT 可以增加异源蛋白质的产量和溶解度。

TAT（47-57）是一种来源于HIV-1 tat蛋白转导结构域（PTD）的细胞可渗透肽（CPP），已被证明可促进核酸进入几种细胞类型。

It is a cell-permeable peptide (CPP) derived from the HIV-1 tat protein transduction domain (PTD), which has been shown to promote the entry of nucleic acids into several cell types.

TFA盐。来源于HIV-1 tat蛋白转导结构域（PTD）的细胞穿透肽已被证明可以促进核酸进入几种细胞类型。对于不同的规格，请使用肽报价工具

TFA Salt. Cell penetrating peptide derived from the HIV-1 tat protein transduction domain (PTD), has been shown to promote the entry of nucleic acids into several cell types. For different specs please use the Peptide Quote Tool

Tat（47-57）是一种穿透细胞的阳离子肽，来源于Tat蛋白的N末端，Tat蛋白是人类免疫缺陷病毒（HIV）中存在的转录蛋白的反式激活剂。具体而言，TAT（47-57）位于TAT肽的富含精氨酸的碱性结构域48-60内，该结构域整体上有三个结构域，其功能是通过转录激活、DNA结合和核转运来帮助HIV。TAT作为一种细胞穿透肽（CPP），有助于细胞摄取分子，因此在转导方法中具有重要作用。这种特性已经通过其允许毒素（如A型肉毒梭菌产生的神经毒素A型肉毒素）非侵入性地穿透皮肤屏障的能力得到了证明。此外，TAT（47-57）可用于将蛋白质、荧光团、螯合剂和DNA递送到靶细胞。

Tat (47-57) is a cell penetrating cationic peptide derived from the N-terminus of the Tat protein, which is a trans-activator of the transcription protein present in the human immunodeficiency virus (HIV). Specifically TAT (47-57) is located within the arginine-rich basic domain 48-60 of the TAT peptide which as a whole has three domains which function to aid HIV through transactivation, DNA binding and nuclear transport. As a cell penetrating peptide (CPP) TAT aids in the cellular uptake of molecules and hence serves a valuable purpose in transduction methods. This property has been demonstrated through its ability of allowing toxins such as the neurotoxin Botulinum neurotoxin Type A, produced by the Clostridium botulinum type A bacteria to penetrate the skin barrier non-invasively. Additionally TAT (47-57) can be used to deliver proteins, fluorophores, chelators and DNA to target cells.

人类免疫缺陷病毒（HIV）病毒外壳转录反式激活蛋白（TAT蛋白）的氨基酸47-57。TAT是一种细胞穿透肽，意味着它能够独立地穿过细胞膜运输到细胞核中。细胞穿透肽（CPP）可用于将其他分子携带到细胞中，因此可用于许多应用。这些应用可能包括：药物递送，其中小药物肽或核酸可以递送到靶细胞中，或者CPP与荧光染料或放射性标记分子等成像剂结合，可用于诊断中的体内或体外成像。该产品以三氟乙酸盐的形式提供

Amino acids 47-57 of the Human Immunodeficiency Virus (HIV) viral coat trans-activator of transcription protein (TAT protein). TAT is a cell penetrating peptide meaning it has the ability to transport itself across cell membranes and into a cells nucleus independently. Cell penetrating peptides (CPPs) can be used to carry other molecules into the cell and therefore can be used in many applications. Such applications may include: drug delivery, where small drug peptides or nucleic acids can be delivered into target cells or where CPPs are conjugated to imaging agents such as fluorescent dyes or radiolabeled molecules they can be used for in vivo or in vitro imaging in diagnostics.\xa0\nThis product is available as a trifluroacetate salt.

这是HIV反式激活蛋白（TAT）最具特征的片段。这种富含精氨酸的TAT肽直接穿透质膜，而不是通过内吞作用，并且已被证明可以促进核酸进入几种细胞类型。

This is the most characterized fragment of the HIV transactivator protein (TAT). This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis, and has been proven to promote the entry of nucleic acids into several cell types.

人类免疫缺陷病毒 1 型反式激活蛋白（47‑57）覆盖一段富含碱性残基的区域，可促进核酸结合与细胞穿透研究。其序列适用于评估基序驱动的摄取行为。研究人员利用其分析与细胞内转运相关的构象柔性。该多肽有助于反式激活区域定位。

HIV-1 tat Protein (47-57) spans a segment rich in basic residues that promote nucleic acid binding and cellular penetration studies. Its sequence supports evaluation of motif-driven uptake behavior. Researchers employ it to analyze conformational flexibility associated with intracellular transport. The peptide aids mapping of transactivation regions.

人类免疫缺陷病毒 1 型反式激活蛋白多肽是一段阳离子序列，用于研究核酸结合与细胞内转运特性。其序列适用于细胞穿透行为与构象适应性分析。研究人员利用其研究与转录激活相关的结构基序。该多肽有助于调控摄取机制建模。

HIV-1 TAT Protein Peptide is a cationic segment used to investigate nucleic acid binding and intracellular transport properties. Its sequence supports analysis of cell-penetrating behavior and conformational adaptability. Researchers employ it to examine structural motifs related to transcriptional activation. The peptide aids modeling of regulatory uptake mechanisms.