26607-15-8_H-Leu-Arg-OH、Leucylarginine_H2N-Leu-Arg-OH_H2N-LR-OH_600+种二肽(Dipeptide)现货

H-Leu-Arg-OH、Leucylarginine
Leucylarginine阻碍L-精氨酸诱导的镇痛感受。

编号：192127

CAS号：26607-15-8

单字母：H2N-LR-OH

编号:	192127
中文名称:	H-Leu-Arg-OH、Leucylarginine
英文名:	Leucylarginine
CAS号:	26607-15-8
单字母:	H2N-LR-OH
三字母:	H2N N端氨基：N-terminal amino group。在肽或多肽链中含有游离a-氨基的氨基酸一端。在表示氨基酸序列时，通常将N端放在肽链的左边。 -Leu L-亮氨酸：leucine。系统命名为(2S)-氨基-4-甲基戊酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：L，Leu。 -Arg L-精氨酸：arginine。系统命名为(2S)-氨基-5-胍基戊酸。在生理条件下带正电荷，为编码氨基酸。是幼小哺乳动物的必需氨基酸。符号：R，Arg。 -OH C端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。
氨基酸个数:	2
分子式:	C₁₂H₂₅N₅O₃
平均分子量:	287.36
精确分子量:	287.2
等电点(PI):	-
pH=7.0时的净电荷数:	1.97
平均亲水性:	0.6
疏水性值:	-0.35
消光系数:	-
标签:	600+种二肽(Dipeptide)现货

Leucylarginine阻碍L-精氨酸诱导的镇痛感受。

Leucylarginine hinders antinociception induced by L-arginine.

H-Leu-Arg-OH acetate salt is a cyclase inhibitor that is used to treat cancer. It has been shown to inhibit soluble guanylate cyclase, which is an enzyme that converts guanosine triphosphate (GTP) into the second messenger molecule, cyclic guanosine monophosphate (cGMP). Inhibition of this enzyme results in a decrease in the production of cGMP and blood pressure. H-Leu-Arg-OH acetate salt also inhibits delta opioid receptors, which are found on the surface of cells in the brain. This drug binds competitively with delta opioid receptors and blocks the effect of endogenous or exogenous ligands such as enkephalins.

DOI	名称
10.1021/acs.jafc.6b02716	Salt Taste Enhancing l-Arginyl Dipeptides from Casein and Lysozyme Released by Peptidases of Basidiomycota	下载
10.1002/1097-0231(20000930)14:18<1654::AID-RCM76>3.0.CO;2-R	Grazing incidence surface-induced dissociation of protonated peptides generated by matrix-assisted laser desorption/ionization	下载
10.1074/jbc.M308983200	Substrate activation of insulin-degrading enzyme (insulysin). A potential target for drug development	下载