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编号：182956

CAS号：170809-51-5

三字母：DPhe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-cyclo(Glu-Ala-His-Lys)-Asn-Arg-Lys-Leu-Nle-Glu-Ile-Ile-CONH2(side chain cyclo)

描 述：The Glu³⁰ to Lys³³ lactam bridge constrains astressin in an α-helical conformation which seems to be responsible for its especially high CRF antagonist activity. Astressin is 100 times more potent than α-helical CRF (9-41) at in

编号：150766

CAS号：142846-71-7

三字母：H2N-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-CONH2

描 述：The galanin antagonist M35, which binds with high specificity and affinity to galanin binding sites, has been administered to rats to test the functional consequences of the galanin receptor blockade in a spatial learning task. The results suggest that ga

编号：114255

CAS号：23815-89-6

三字母：H2N-Arg-Pro-Pro-Gly-Phe-OH

描 述：The fragment RPPGF and the two dipeptides Phe-Arg and Ser-Pro are obtained by action of angiotensin-converting enzyme (ACE) on bradykinin. RPPGF inhibits thrombin-induced platelet activation, and in high concentration, the pentapeptide inhibits thrombin-i

编号：128066

CAS号：1802084-26-9

三字母：H2N-Asp-Ala-Glu-Phe-Arg-Arg-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH

描 述：The English (H6R) mutation of β-amyloid peptides accelerates fibrillation without increasing protofibril formation. Ono et al. showed that the English and Tottori mutations alter Abeta assembly at its earliest stages, monomer folding and oligomerizat

编号：129894

CAS号：138398-61-5

三字母：H2N-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-CONH2

描 述：The effect of IAPP (8-37) (mouse, rat), an amylin receptor antagonist, on the ANP release was attenuated in streptozotocin-treated rats.

编号：179290

CAS号：144410-00-4

三字母：H2N-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gln-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH

描 述：The Dutch mutation (E22Q) of amyloid β-peptide aggregates more readily than the wild-type peptide and the resulting fibrils show increased neurotoxicity. The mutant peptide E22Q induced apoptosis of cerebral endothelial cells at a concentration of 25

编号：179968

CAS号：2578-58-7

三字母：H2N-His-Gly-OH

描 述：The dipeptide L-histidylglycine forms ESR-active Cu(II) complexes.

编号：164752

CAS号：188968-51-6/199807-35-7

三字母：cyclo(Arg-Gly-Asp-DPhe-(NMe)Val)(main chain cyclo)

描 述：The cyclic RGD peptide cilengitide is a potential cancer drug. Cilengitide is under investigation for the treatment of glioblastoma, where it may act by inhibiting angiogenesis, and influencing tumor invasion and proliferation.

编号：171768

CAS号：131580-10-4

三字母：H2N-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-OH

描 述：The Cu²⁺ complex of this soluble amyloid β-protein fragment showed significant oxidative activities toward the catechol-like substrate 1,2,3-trihydroxylbenzene (pyrogallol) and plasmid DNA cleavage. The N-terminal Aβ fragments Aβ1-14,

编号：196599

CAS号：287399-97-7

三字母：Ac-His-His-Gly-His-OH

描 述：The Cu(II) complex of Ac-HHGH can serve as a model for copper-containing oxidases as catecholases.