二肽 Arg-Phe 模拟 FMRF 酰胺的血液动力学效应。通过交感神经系统的中枢刺激，这两种肽都增加了麻醉大鼠的血压和心率，RF 的效力大约是其 4 倍。
编号：192466
CAS号：2047-13-4
单字母：H2N-RF-OH
| 编号: | 192466 |
| 中文名称: | 二肽Arg-Phe |
| 英文名: | Arg-Phe |
| CAS号: | 2047-13-4 |
| 单字母: | H2N-RF-OH |
| 三字母: | H2N N端氨基 -Arg精氨酸 -Phe苯丙氨酸 -OHC端羧基 |
| 氨基酸个数: | 2 |
| 分子式: | C15H23N5O3 |
| 平均分子量: | 321.37 |
| 精确分子量: | 321.18 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 1.97 |
| 平均亲水性: | 0.25 |
| 疏水性值: | -0.85 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 二肽(Dipeptide) |
The dipeptide Arg-Phe mimics the haemodynamic effects of FMRF amide. Both peptides increased blood pressure and heart rate in anaesthesized rats by central stimulation of the sympathetic nervous system, RF being approximately 4 fold more potent.
| DOI | 名称 | |
|---|---|---|
| 10.1016/s0006-291x(05)81237-9 | FMRF-amide and L-Arg-L-Phe increase blood pressure and heart rate in the anaesthetised rat by central stimulation of the sympathetic nervous system | 下载 |
| 10.1016/j.jasms.2005.02.008 | Stereoselective discrimination and quantification of arginine and N-blocked arginine enantiomers by formation and dissociation of calcium-mediated diastereomeric trimer complexes with a chiral reference compound using electrospray ionization-ion trap tandem mass spectrometry | 下载 |
| 10.1016/0014-5793(91)81434-a | On the substrate specificity of nitric oxide synthase | 下载 |
