编号:123036
CAS号:
三字母:H2N-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-NH2(Disulfide Bridge:Cys1-Cys15 & Cys3-Cys11)
描 述:血管收缩剂
编号:114169
CAS号:133551-97-0
三字母:Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-Ile-Asn-Thr-Pro-Glu-Gln-Thr-Val-Pro-Tyr-Gly-Leu-Ser-Asn-Tyr-Arg-Gly-Ser-Phe-Arg-NH2 (Disulfide bonds between Cys¹ and Cys¹⁵/Cys³ and Cys¹¹)
描 述:尽管与Big ET-1相比,人类大内皮素3的动脉压升高,但功效和功效却有所降低。
编号:122468
CAS号:121377-67-1
三字母:H2N-His-Leu-Asp-Ile-Ile-Trp-OH
描 述:发现内皮素C-末端片段HLDIIW在ET-B受体上是完全激动剂,而在ET-A受体上是无活性的或弱活性的。
编号:155598
CAS号:174283-52-4
三字母:H2N-Ile-Asn-Thr-Pro-Glu-Gln-Thr-Val-Pro-Tyr-Gly-Leu-Ser-Asn-Tyr-Arg-Gly-Ser-Phe-Arg-NH2
描 述:内源性肽片段首先从牛肾上腺髓质中分离出来。BAM-15 是感觉神经元特异性受体的选择性激动剂(SNSR3 和 SNSR4 的 EC₅₀ 值分别为 28 和 14 nM)。
编号:176540
CAS号:120796-99-8
三字母:H2N-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Ile-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Ser-Arg-Ser-OH(Disulfide Bridge:Cys1-Cys15 & Cys3-Cys11)
描 述:The big endothelins comprise residues 53-90 (human big ET-1) and 53-91 (porcine big ET-1) of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (ET-1), both peptides show less vasoconstrictor activity in vitro, but similar pr
编号:132940
CAS号:153982-38-8
三字母:cyclo(DSer-Pro-DVal-Leu-DTrp)(main chain cyclo)
描 述:JKC302,高效ET-A受体拮抗剂。
编号:135857
CAS号:136553-96-3
三字母:cyclo(DAsp-Pro-DIle-Leu-DTrp)(main chain cyclo)
描 述:JKC-301,一种高效的ET-A受体拮抗剂。
编号:185718
CAS号:144602-02-8
三字母:H2N-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH
描 述:IRL1038 inhibits ET-B receptor-mediated contraction of guinea-pig ileal and tracheal smooth muscle without any significant agonist activity, but does not affect the ET-A receptor-mediated contraction of rat aortic smooth muscle.
编号:120467
CAS号:120796-97-6
三字母:Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Arg-Ser(Disulfide bonds between Cys¹ and Cys¹⁵/Cys³ and Cys¹¹)
描 述:Human Big ET-1 comprises residues 53-90 of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (hET-1), the peptide show less vasoconstrictor activity in vitro, but similar pressor effects in vivo. Former CAS-number 121014-53-
编号:147759
CAS号:
三字母:Ac-His-Leu-Asp-Ile-Ile-Trp-OH
描 述:ETA/ ETB受体激动剂,血管收缩剂。