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75539-79-6,三肽Cbz-DPhe-Phe-GLY,Cbz-DPhe-Phe-Gly-COOH,Z-DPhe-FG-OH,杭州专肽生物的产品

三肽Cbz-DPhe-Phe-GLY

A high level of inhibition of virus replication was obtained with this peptide, which resembles a region of a viral polypeptide.

编号:190051

CAS号:75539-79-6

单字母:Z-fFG-OH

纠错
  • 编号:190051
    中文名称:三肽Cbz-DPhe-Phe-GLY
    英文名:Z-D-Phe-Phe-Gly-OH
    英文同义词:Fusion Inhibitory Peptide, FIP, Virus Replication Inhibitory Peptide
    CAS号:75539-79-6
    单字母:Z-fFG-OH
    三字母:Cbz

    N端Cbz保护

    -DPhe

    D型笨丙氨酸

    -Phe

    苯丙氨酸

    -Gly

    甘氨酸

    -OH

    C端羧基

    氨基酸个数:3
    分子式:C28H29O6N3
    平均分子量:503.55
    精确分子量:503.21
    等电点(PI):-
    pH=7.0时的净电荷数:-
    平均亲水性:-2.5
    疏水性值:1.73
    外观与性状:白色粉末状固体
    消光系数:-
    来源:人工化学合成,仅限科学研究使用,不得用于人体。
    纯度:95%、98%
    盐体系:可选TFA、HAc、HCl或其它
    储存条件:负80℃至负20℃
    标签:D型氨基酸肽    CBZ修饰肽    三肽    病毒学   

  • A high level of inhibition of virus replication was obtained with this peptide, which resembles a region of a viral polypeptide.

    很多蛋白在细胞中非常容易被降解,或被标记,进而被选择性地破坏。但含有部分D型氨基酸的多肽则显示了很强的抵抗蛋白酶降解能力。

  • DOI名称
    10.1128/jvi.76.15.7460-7467.2002Efficiency of measles virus entry and dissemination through different receptors下载
    10.1128/jvi.77.7.4181-4190.2003Mutations in the putative HR-C region of the measles virus F2 glycoprotein modulate syncytium formation下载
    10.1128/JVI.80.7.3477-3486.2006Measles virus targets DC-SIGN to enhance dendritic cell infection下载
    10.1111/j.1462-5822.2006.00752.xMeasles virus induces expression of SIP110, a constitutively membrane clustered lipid phosphatase, which inhibits T cell proliferation下载
    10.1016/j.virol.2007.02.033Neurokinin-1 enables measles virus trans-synaptic spread in neurons下载
    10.3748/wjg.v13.i22.3063In situ tumor vaccination with adenovirus vectors encoding measles virus fusogenic membrane proteins and cytokines下载
    10.1371/journal.ppat.1000049DC-SIGN and CD150 have distinct roles in transmission of measles virus from dendritic cells to T-lymphocytes下载
    10.1021/bi801513pMeasles virus entry inhibitors: a structural proposal for mechanism of action and the development of resistance下载
    10.1128/AAC.00503-09Target analysis of the experimental measles therapeutic AS-136A下载
    10.1128/JVI.01195-09Probing the spatial organization of measles virus fusion complexes下载
    10.1016/j.vaccine.2011.04.079Towards ambient temperature-stable vaccines: the identification of thermally stabilizing liquid formulations for measles virus using an innovative high-throughput infectivity assay下载
    10.1002/eji.201041305Human Langerhans cells capture measles virus through Langerin and present viral antigens to CD4⁺ T cells but are incapable of cross-presentation下载
    10.1089/hum.2011.146Retargeting vesicular stomatitis virus using measles virus envelope glycoproteins下载
    10.1128/JVI.01945-13A stabilized headless measles virus attachment protein stalk efficiently triggers membrane fusion下载
    10.1007/BF01114759Virus replication inhibitory peptide inhibits the conversion of phospholipid bilayers to the hexagonal phase下载
    10.1016/0042-6822(80)90168-3Specific inhibition of paramyxovirus and myxovirus replication by oligopeptides with amino acid sequences similar to those at the N-termini of the F1 or HA2 viral polypeptides下载
    10.1038/mt.2009.39Intravascularly administered RGD-displaying measles viruses bind to and infect neovessel endothelial cells in vivo下载
    10.1016/j.exphem.2013.01.010Enhancing cytokine-induced killer cell therapy of multiple myeloma下载
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