Component of coffee flavor
编号：126619
CAS号：2854-40-2
单字母：cyclo(PV)(main chain cyclo)
| 编号: | 126619 |
| 中文名称: | 环二肽cyclo(Pro-Val) |
| 英文名: | c(Pro-Val) |
| 英文同义词: | c(Val-Pro)、cyclo(Val-Pro) |
| CAS号: | 2854-40-2 |
| 单字母: | cyclo(PV)(main chain cyclo) |
| 三字母: | cyclo(Pro-Val)(main chain cyclo) |
| 氨基酸个数: | 2 |
| 分子式: | C10H16N2O2 |
| 平均分子量: | 196.25 |
| 精确分子量: | 196.12 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 0.97 |
| 平均亲水性: | -1.5 |
| 疏水性值: | 1.3 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 修饰类型: | 酰胺键成环 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 环二肽 现货多肽 |
Component of coffee flavor
环二肽又叫2,5-二酮哌嗪的衍生物,作为环肽成员中最小的一类环肽，专肽生物有部分环二肽的现货，也可以根据实验需求，定制含D型与L型，S与R构型的氨基酸。
Cyclo(Pro-Val) and other Pro-containing diketopiperazines were detected in roasted coffee. The amount of these compounds increases with the intensity of roasting, they contribute to the bitterness of taste. The bitter-tasting cyclodipeptide has also been detected in other foodstuffs as cocoa, chocolate, beef, and cheese. Cyclo(Pro-Val), which shows antifungal activity, has also been isolated from microorganisms and further natural sources.
R.Ortiz-Castro et al., Proc. Natl. Acad. Sci. USA, 108, 7253 (2011)；http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21482761
L.Yang et al., Tetrahedron Lett., 43, 6545 (2002)
M.Ginz and U.H.Engelhardt, Eur. Food . Res. Technol., 213, 8 (2001)
