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136553-81-6,BQ-123,cyclo(Trp-DAsp-Pro-DVal-LeuTrp-DAsp-Pro-DVal-Leu),,杭州专肽生物的产品

BQ-123

BQ-123是一种有效的内皮素拮抗剂,对ET-A受体亚型具有高选择性。

编号:164076

CAS号:136553-81-6

单字母:

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  • 编号:164076
    中文名称:BQ-123
    CAS号:136553-81-6
    三字母:cyclo(Trp-DAsp-Pro-DVal-LeuTrp-DAsp-Pro-DVal-Leu)
    来源:人工化学合成,仅限科学研究使用,不得用于人体。
    储存条件:负80℃至负20℃
    标签:大内皮素及类似物   

  • BQ-123 is a potent endothelin antagonist with high selectivity for the ET-A receptor subtype.

  • DOI名称
    10.1016/0014-5793(92)80390-3Conformational study of cyclo[D-Trp-D-Asp-Pro-D-Val-Leu], an endothelin-A receptor-selective antagonist下载
    10.1016/0024-3205(92)90331-iBiological profiles of highly potent novel endothelin antagonists selective for the ETA receptor下载
    10.1016/0014-5793(92)80451-lA novel ETA antagonist (BQ-123) inhibits endothelin-1-induced phosphoinositide breakdown and DNA synthesis in rat vascular smooth muscle cells下载
    10.1016/0006-291x(92)91710-8The endothelin receptor antagonist, BQ-123, inhibits angiotensin II-induced contractions in rabbit aorta下载
    10.1016/0922-4106(92)90109-9The selective endothelin ETA receptor antagonist BQ123 antagonizes endothelin-1-mediated mitogenesis下载
    10.1016/0006-291x(92)91223-dBQ-123, cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu), is a non-competitive antagonist of the actions of endothelin-1 in SK-N-MC human neuroblastoma cells下载
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