编号: | 200208 |
中文名称: | 八肽pGlu-HWSYLLRP-NHEt |
CAS号: | 54785-87-4 |
单字母: | Pyr-HWSYLLRP-NHEt |
三字母: | Pyr 焦谷氨酸 -His组氨酸 -Trp色氨酸 -Ser丝氨酸 -Tyr酪氨酸 -Leu亮氨酸 -Leu亮氨酸 -Arg精氨酸 -Pro脯氨酸 -NHEtC端乙胺基化修饰 |
氨基酸个数: | 8 |
分子式: | C59H84N15O12 |
平均分子量: | 1195.39 |
精确分子量: | 1194.64 |
等电点(PI): | - |
pH=7.0时的净电荷数: | 2.24 |
平均亲水性: | -1.0857142857143 |
疏水性值: | -0.54 |
消光系数: | 6990 |
来源: | 人工化学合成,仅限科学研究使用,不得用于人体。 |
储存条件: | 负80℃至负20℃ |
标签: | 亮丙瑞林系列 垂体和下丘脑激素 |
Impurity C of the Leuprorelin Ph. Eur. monograph.
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10.1016/s0168-3659(03)00366-3 | Monitoring of peptide acylation inside degrading PLGA microspheres by capillary electrophoresis and MALDI-TOF mass spectrometry | 下载 |
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10.1208/pt060242 | Development of a dialysis in vitro release method for biodegradable microspheres | 下载 |
10.1208/pt060470 | A model-dependent approach to correlate accelerated with real-time release from biodegradable microspheres | 下载 |
10.1080/07357900600629591 | Effect of leuprolide and cetrorelix on cell growth, apoptosis, and GnRH receptor expression in primary cell cultures from human prostate carcinoma | 下载 |
10.2165/00002512-199101060-00008 | Leuprorelin. A review of its pharmacology and therapeutic use in prostatic disorders | 下载 |
10.1002/jps.21415 | Changes in morphology of in situ forming PLGA implant prepared by different polymer molecular weight and its effect on release behavior | 下载 |
10.1007/s00726-010-0549-8 | Structural elucidation of Leuprolide and its analogues in solution: insight into their bioactive conformation | 下载 |
10.4155/bio.11.39 | Bioanalytical determination of unstable endogenous small peptides: RFRP3 and its metabolites in rat blood | 下载 |
10.1002/jps.23029 | Effect of agitation regimen on the in vitro release of leuprolide from poly(lactic-co-glycolic) acid microparticles | 下载 |
10.1016/j.carbpol.2012.05.028 | S-protected thiolated chitosan: synthesis and in vitro characterization | 下载 |
10.1186/2008-2231-21-57 | In-vitro/In-vivo comparison of leuprolide acetate release from an in-situ forming plga system | 下载 |