编号：200324
CAS号：68893-82-3
单字母：H2N-SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFVALGAPLAPRDAGSQRPRKKEDNVLVESH-OH
| 编号: | 200324 |
| 中文名称: | 甲状旁腺激素 pTH (1-84) (human) |
| 英文名: | Parathyroid Hormone(1-84) (human) |
| CAS号: | 68893-82-3 |
| 单字母: | H2N-SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFVALGAPLAPRDAGSQRPRKKEDNVLVESH-OH |
| 三字母: | H2N N端氨基 -Ser丝氨酸 -Val缬氨酸 -Ser丝氨酸 -Glu谷氨酸 -Ile异亮氨酸 -Gln谷氨酰胺 -Leu亮氨酸 -Met甲硫氨酸 -His组氨酸 -Asn天冬酰胺 -Leu亮氨酸 -Gly甘氨酸 -Lys赖氨酸 -His组氨酸 -Leu亮氨酸 -Asn天冬酰胺 -Ser丝氨酸 -Met甲硫氨酸 -Glu谷氨酸 -Arg精氨酸 -Val缬氨酸 -Glu谷氨酸 -Trp色氨酸 -Leu亮氨酸 -Arg精氨酸 -Lys赖氨酸 -Lys赖氨酸 -Leu亮氨酸 -Gln谷氨酰胺 -Asp天冬氨酸 -Val缬氨酸 -His组氨酸 -Asn天冬酰胺 -Phe苯丙氨酸 -Val缬氨酸 -Ala丙氨酸 -Leu亮氨酸 -Gly甘氨酸 -Ala丙氨酸 -Pro脯氨酸 -Leu亮氨酸 -Ala丙氨酸 -Pro脯氨酸 -Arg精氨酸 -Asp天冬氨酸 -Ala丙氨酸 -Gly甘氨酸 -Ser丝氨酸 -Gln谷氨酰胺 -Arg精氨酸 -Pro脯氨酸 -Arg精氨酸 -Lys赖氨酸 -Lys赖氨酸 -Glu谷氨酸 -Asp天冬氨酸 -Asn天冬酰胺 -Val缬氨酸 -Leu亮氨酸 -Val缬氨酸 -Glu谷氨酸 -Ser丝氨酸 -His组氨酸 -OHC端羧基 |
| 氨基酸个数: | 63 |
| 分子式: | C314H513N99O92S2 |
| 平均分子量: | 7211.17 |
| 精确分子量: | 7206.79 |
| 等电点(PI): | 10.61 |
| pH=7.0时的净电荷数: | 3.93 |
| 平均亲水性: | 0.33684210526316 |
| 疏水性值: | -0.7 |
| 消光系数: | 5500 |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 再生医学 |
| DOI | 名称 | |
|---|---|---|
| 10.1530/eje.0.1470123 | Origin of parathyroid hormone (PTH) fragments detected by intact-PTH assays | 下载 |
| 10.1046/j.1523-1755.2002.00616.x | Circulating inhibitor of gonadotropin releasing hormone secretion by hypothalamic neurons in uremia | 下载 |
| 10.1345/aph.1G146 | Parathyroid hormone (1-84) and treatment of osteoporosis | 下载 |
| 10.1111/j.1523-1755.2005.00493.x | Structure of non-(1-84) PTH fragments secreted by parathyroid glands in primary and secondary hyperparathyroidism | 下载 |
| 10.1038/sj.ki.5001606 | Inter-method variability in PTH measurement: implication for the care of CKD patients | 下载 |
| 10.1515/CCLM.2007.017 | Analytical validation of the new version of the Liaison N-Tact PTH assay | 下载 |
| 10.1210/en.2007-0734 | Targeted deletion of a distant transcriptional enhancer of the receptor activator of nuclear factor-kappaB ligand gene reduces bone remodeling and increases bone mass | 下载 |
| 10.1016/j.mce.2009.03.024 | Parathyroid hormone suppresses insulin signaling in adipocytes | 下载 |
| 10.1002/jbmr.145 | Continuous elevation of PTH increases the number of osteoblasts via both osteoclast-dependent and -independent mechanisms | 下载 |
| 10.1002/jcp.22844 | Amelioration of type I diabetes-induced osteoporosis by parathyroid hormone is associated with improved osteoblast survival | 下载 |
| 10.1161/HYPERTENSIONAHA.111.172890 | Hypercalcemia reduces plasma renin via parathyroid hormone, renal interstitial calcium, and the calcium-sensing receptor | 下载 |
| 10.1371/journal.pone.0040242 | Measuring parathyroid hormone (PTH) in patients with oxidative stress--do we need a fourth generation parathyroid hormone assay? | 下载 |
| 10.1021/ja306637u | Engineering of therapeutic polypeptides through chemical synthesis: early lessons from human parathyroid hormone and analogues | 下载 |
| 10.1002/emmm.201302979 | Decreased bone formation and increased osteoclastogenesis cause bone loss in mucolipidosis II | 下载 |
| 10.1210/endo-117-5-1962 | Biological activities of synthetic human parathyroid hormone (PTH) 1-84 relative to natural bovine 1-84 PTH in two different in vivo bioassay systems | 下载 |
| 10.1016/0006-291x(83)90807-0 | Solution synthesis of [ASN76]-human parathyroid hormone (1-84) | 下载 |
| 10.1073/pnas.78.12.7365 | Nucleotide sequence of cloned cDNAs encoding human preproparathyroid hormone | 下载 |
| 10.1210/endo.138.8.5315 | Parathyroid hormone (PTH 1-34) regulation of rat osteocalcin gene transcription | 下载 |
